HAMAP rule MF_04134
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_04134 |
| Accession | MF_04134 |
| Dates | 11-JAN-2019 (Created)
01-JUN-2023 (Last updated, Version 7) |
| Name | GT_LAMBD |
| Scope(s) |
Viruses Caudoviricetes |
| Template(s) | O64329; [ Recover all ] |
| Triggered by |
HAMAP; MF_04134 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| case <Feature:PF06223> | |
| Identifier | GT |
| Protein name | RecName: Full=Tail assembly protein GT; AltName: Full=Gene product 15; Short=gp15; AltName: Full=Gene product GT; Short=gpGT; AltName: Full=Minor tail protein GT; |
| else | |
| Identifier | G |
| Protein name | RecName: Full=Tail assembly protein G; AltName: Full=Gene product G; Short=gpG; AltName: Full=Minor tail protein G; AltName: Full=Tail assembly chaperone; Short=TAC; |
| end case | |
Comments
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| FUNCTION | Promotes tail assembly by creating a scaffold for the tail tube proteins. Tail assembly proteins G and GT probably wrap the linear tape measure protein to create a tail assembly scaffold. This allows the polymerization of the tail tube protein, during which G and GT are released, therefore they are absent in the mature virion. The tail assembly protein GT is produced by a rare -1 ribosomal frameshift. The ratio of translated G/GT is about 20, and this ratio is important for proper tail assembly. |
| SUBCELLULAR LOCATION | Host cytoplasm. |
| SIMILARITY | Belongs to the lambda-like tail assembly protein family. |
| case <Feature:PF06223> | |
| SUBUNIT | Interacts (via C-terminus) with tail tube protein. Interacts (via N-terminus) with the tail assembly protein G and the tape measure protein. |
| else | |
| SUBUNIT | Interacts with the tail assembly protein GT and tape measure protein. |
| end case | |
Keywords
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Gene Ontology
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| GO:0030430; Cellular component:host cell cytoplasm |
| GO:0098003; Biological process:viral tail assembly |
Cross-references
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| Pfam | PF06894; Phage_TAC_2; 1; |
| Pfam | PF06223; Phage_tail_T; 0-1; |
| NCBIfam | TIGR01715; phage_lam_T; 0-1; |
| NCBIfam | TIGR01674; phage_lambda_G; 1; |
| General | Coiled_coil; -; 0-unlimited; |
Features
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Additional information
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| Size range | 90-279 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |