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HAMAP rule MF_04134

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General rule information [?]

Accession MF_04134
Dates 11-JAN-2019 (Created)
1-JUN-2023 (Last updated, Version 6)
Name GT_LAMBD
Scope(s) Viruses
Caudoviricetes
Template(s) O64329 (GT_BPN15); [ Recover all ]
Triggered by HAMAP; MF_04134 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

case <Feature:PF06223>
Identifier GT
Protein name RecName: Full=Tail assembly protein GT;
AltName: Full=Gene product 15;
                 Short=gp15;
AltName: Full=Gene product GT;
                 Short=gpGT;
AltName: Full=Minor tail protein GT;
else
Identifier G
Protein name RecName: Full=Tail assembly protein G;
AltName: Full=Gene product G;
                 Short=gpG;
AltName: Full=Minor tail protein G;
AltName: Full=Tail assembly chaperone;
                 Short=TAC;
end case

Comments [?]

FUNCTIONPromotes tail assembly by creating a scaffold for the tail tube proteins. Tail assembly proteins G and GT probably wrap the linear tape measure protein to create a tail assembly scaffold. This allows the polymerization of the tail tube protein, during which G and GT are released, therefore they are absent in the mature virion. The tail assembly protein GT is produced by a rare -1 ribosomal frameshift. The ratio of translated G/GT is about 20, and this ratio is important for proper tail assembly.
SUBCELLULAR LOCATIONHost cytoplasm.
SIMILARITYBelongs to the lambda-like tail assembly protein family.
case <Feature:PF06223>
SUBUNITInteracts (via C-terminus) with tail tube protein. Interacts (via N-terminus) with the tail assembly protein G and the tape measure protein.
else
SUBUNITInteracts with the tail assembly protein GT and tape measure protein.
end case

Keywords [?]


Gene Ontology [?]

GO:0030430; Cellular component:host cell cytoplasm
GO:0098003; Biological process:viral tail assembly

Cross-references [?]

Pfam PF06894; Phage_TAC_2; 1;
Pfam PF06223; Phage_tail_T; 0-1;
NCBIfam TIGR01715; phage_lam_T; 0-1;
NCBIfam TIGR01674; phage_lambda_G; 1;
General Coiled_coil; -; 0-unlimited;

Features [?]


Additional information [?]

Size range 90-279 amino acids
Related rules None
Fusion Nter: None Cter: None



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