HAMAP rule MF_04160
General rule information
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| Accession | MF_04160 |
| Dates | 6-APR-2021 (Created)
20-APR-2021 (Last updated, Version 2) |
| Name | NUCL_HEAD_T4 |
| Scope(s) |
Viruses |
| Template(s) | P15075 (HDNUC_BPT4); [ Recover all ] |
| Triggered by |
HAMAP; MF_04160 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | HDNUC |
| Protein name | RecName: Full=Head completion nuclease; EC=3.1.-.-; |
Comments
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| FUNCTION | During phage morphogenesis, plays an essential role in the head-tail joining step. The associated nuclease activity is essential for morphogenesis, possibly by cleaving packaged DNA to enable the joining of heads to tails. Displays both exo- and endonuclease activity. |
| SIMILARITY | Belongs to the Caudovirales head completion nuclease family. |
Keywords
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Gene Ontology
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| GO:0004527; Molecular function:exonuclease activity |
| GO:0004519; Molecular function:endonuclease activity |
Cross-references
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| Pfam | PF08722; Tn7_Tnp_TnsA_N; 0-1; |
Features
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| From: HDNUC_BPT4 (P15075) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 29 | 29 | E | |||||||||
| ACT_SITE | 68 | 68 | D | |||||||||
| ACT_SITE | 84 | 84 | K | |||||||||
Additional information
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| Size range | 120-220 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |