HAMAP rule MF_04203
General rule information
[?]
| Accession | MF_04203 |
| Dates | 26-MAR-2018 (Created)
29-SEP-2022 (Last updated, Version 4) |
| Name | GAMMA_CORONA_M |
| Scope(s) |
Viruses Gammacoronavirus |
| Template(s) | P69601 (VME1_IBVB); [ Recover all ] |
| Triggered by |
HAMAP; MF_04203 (Get profile general information and statistics) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
| Identifier | VME1 |
| Protein name | RecName: Full=Membrane protein; Short=M protein; AltName: Full=E1 glycoprotein; AltName: Full=Matrix glycoprotein; AltName: Full=Membrane glycoprotein; |
| Gene name | Name=M; |
Comments
[?]
| FUNCTION | Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins. |
| SUBUNIT | Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus. |
| SUBCELLULAR LOCATION | Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer. |
| SIMILARITY | Belongs to the gammacoronaviruses M protein family. |
Keywords
[?]
| Glycoprotein |
| Host Golgi apparatus |
| Host membrane |
| Membrane |
| Transmembrane |
| Transmembrane helix |
| Viral envelope protein |
| Viral matrix protein |
| Virion |
Gene Ontology
[?]
| GO:0030430; Cellular component:host cell cytoplasm |
| GO:0044178; Cellular component:host cell Golgi membrane |
| GO:0016020; Cellular component:membrane |
| GO:0019031; Cellular component:viral envelope |
| GO:0055036; Cellular component:virion membrane |
| GO:0039660; Molecular function:structural constituent of virion |
Cross-references
[?]
| Pfam | PF01635; Corona_M; 1; |
| General | Transmembrane; -; 3; |
Features
[?]
| From: VME1_IBVB (P69601) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| TOPO_DOM | Nter | 20 | /note="Virion surface" | |||||||||
| TRANSMEM | 21 | 41 | /note="Helical" | |||||||||
| TOPO_DOM | 42 | 51 | /note="Intravirion" | |||||||||
| TRANSMEM | 52 | 72 | /note="Helical" | |||||||||
| TOPO_DOM | 73 | 77 | /note="Virion surface" | |||||||||
| TRANSMEM | 78 | 98 | /note="Helical" | |||||||||
| TOPO_DOM | 99 | Cter | /note="Intravirion" | |||||||||
Additional information
[?]
| Size range | 223-230 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |