HAMAP rule MF_04203
General rule information
[?]
Accession | MF_04203 |
Dates | 26-MAR-2018 (Created)
29-SEP-2022 (Last updated, Version 4) |
Name | GAMMA_CORONA_M |
Scope(s) |
Viruses Gammacoronavirus |
Template(s) | P69601 (VME1_IBVB); [ Recover all ] |
Triggered by |
HAMAP; MF_04203 (Get profile general information and statistics) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier | VME1 |
Protein name | RecName: Full=Membrane protein; Short=M protein; AltName: Full=E1 glycoprotein; AltName: Full=Matrix glycoprotein; AltName: Full=Membrane glycoprotein; |
Gene name | Name=M; |
Comments
[?]
FUNCTION | Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins. |
SUBUNIT | Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus. |
SUBCELLULAR LOCATION | Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer. |
SIMILARITY | Belongs to the gammacoronaviruses M protein family. |
Keywords
[?]
Glycoprotein |
Host Golgi apparatus |
Host membrane |
Membrane |
Transmembrane |
Transmembrane helix |
Viral envelope protein |
Viral matrix protein |
Virion |
Gene Ontology
[?]
GO:0030430; Cellular component:host cell cytoplasm |
GO:0044178; Cellular component:host cell Golgi membrane |
GO:0016020; Cellular component:membrane |
GO:0019031; Cellular component:viral envelope |
GO:0055036; Cellular component:virion membrane |
GO:0039660; Molecular function:structural constituent of virion |
Cross-references
[?]
Pfam | PF01635; Corona_M; 1; |
General | Transmembrane; -; 3; |
Features
[?]
From: VME1_IBVB (P69601) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
TOPO_DOM | Nter | 20 | /note="Virion surface" | |||||||||
TRANSMEM | 21 | 41 | /note="Helical" | |||||||||
TOPO_DOM | 42 | 51 | /note="Intravirion" | |||||||||
TRANSMEM | 52 | 72 | /note="Helical" | |||||||||
TOPO_DOM | 73 | 77 | /note="Virion surface" | |||||||||
TRANSMEM | 78 | 98 | /note="Helical" | |||||||||
TOPO_DOM | 99 | Cter | /note="Intravirion" |
Additional information
[?]
Size range | 223-230 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |