HAMAP

Accession	MF_00551
Dates	29-APR-2002 (Created) 10-OCT-2011 (Last updated, Version 19)

Data class

Protein

Predictors

HAMAP; MF_00551; [distribution of match scores in UniProtKB];[seed alignment for MF_00551]

Names

Uridine_kinase

Identifier

URK

Protein name

RecName: Full=Uridine kinase; EC=2.7.1.48; AltName: Full=Cytidine monophosphokinase; AltName: Full=Uridine monophosphokinase;

Gene name

udk

CATALYTIC ACTIVITY: ATP + uridine = ADP + UMP.

CATALYTIC ACTIVITY: ATP + cytidine = ADP + CMP.

PATHWAY: Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.

PATHWAY: Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the uridine kinase family.

Pfam	PF00485; PRK; 1;
PRINTS	PR00478; PHRIBLKINASE; 1; PR00988; URIDINKINASE; 1;
TIGRFAMs	TIGR00235; Udk; 1;

Cytoplasm, Transferase, Kinase, ATP-binding, Nucleotide-binding.

GO:0005524; Molecular function: ATP binding.
GO:0004849; Molecular function: uridine kinase activity.
GO:0008655; Biological process: pyrimidine-containing compound salvage.
GO:0005737; Cellular component: cytoplasm.

From: URK_ECOLI (P0A8F4)
Key		From		To		Description		Condition		FTGroup
NP_BIND		15		22		ATP (Potential)		G-[GA]-[ST]-[GAC]-[GSA]-G-K-[ST]

Size range:	205-225 amino acids
Related UniRules:	None
Template:	P0A8F4 (URK_ECOLI)
Scope:	Bacteria Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None