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| HAMAP annotation rule: MF_01250 |
| Accession | MF_01250 |
| Dates | 3-AUG-2004 (Created) 25-NOV-2009 (Last updated, Version 7) |
| Data class | Protein |
| Predictors | HAMAP; MF_01250; [distribution of match scores in UniProtKB];[seed alignment for MF_01250] |
| Names | Pyrophosphat_PpaX |
| Identifier | PPAX |
case <OC:Bacillales>
| Protein name |
|
end case
case not <OC:Bacillales>
| Protein name |
|
end case
| Gene name | ppaX |
case <OC:Bacillales>
FUNCTION: Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool (By similarity).
end case
CATALYTIC ACTIVITY: Diphosphate + H(2)O = 2 phosphate.
COFACTOR: Magnesium (Potential).
SIMILARITY: Belongs to the HAD-like hydrolase superfamily. PpaX family.
| Pfam |
PF00702; Hydrolase; 1; |
| PRINTS |
PR00413; HADHALOGNASE; 1; |
| TIGRFAMs |
TIGR01549; HAD-SF-IA-v1; 1; TIGR01509; HAD-SF-IA-v3; 1; TIGR02009; PGMB-YQAB-SF; 1; |
GO:0000287; Molecular function: magnesium ion binding.
GO:0004427; Molecular function: inorganic diphosphatase activity.
GO:0004427; Molecular function: inorganic diphosphatase activity.
| From: PPAX_BACSU (Q9JMQ2) | ||||||||||
| Key | From | To | Description | Condition | FTGroup | |||||
| ACT_SITE | 12 | 12 | Nucleophile (By similarity) | D | ||||||
| Size range: | 214-220 amino acids |
| Related UniRules: | None |
| Template: | Q9JMQ2 (PPAX_BACSU) |
| Scope: | Bacteria; Bacillales Bacteria; Clostridia |
| Fusion: | Nter: None; Cter: None |
| Duplicate: | None |
| Plasmid encoded: | None |
| Comments: | In Bacillales, the gene corresponding to this protein is located in the proximity of hprK gene which encodes HPr kinase/phosphorylase. |
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