HAMAP annotation rule MF_01856
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Accession MF_01856
Dates 5-FEB-2009 (Created)
19-AUG-2011 (Last updated, Version 6)
Name 16SrRNA_methyltr_B
Scope Bacteria; Enterobacteriales
Triggered by



Identifier
RSMB
Protein name
RecName: Full=Ribosomal RNA small subunit methyltransferase B;
EC=2.1.1.176;
AltName: Full=16S rRNA m5C967 methyltransferase;
AltName: Full=rRNA (cytosine-C(5)-)-methyltransferase RsmB;
Gene name
rsmB, sun


FUNCTION Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA (By similarity).
CATALYTIC ACTIVITY S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.
SUBCELLULAR LOCATION Cytoplasm (Potential).
SIMILARITY Belongs to the methyltransferase superfamily. RsmB/NOP family.


Cytoplasm
Methyltransferase
RNA-binding
rRNA processing
S-adenosyl-L-methionine
Transferase


GO:0016434; Molecular function: rRNA (cytosine) methyltransferase activity.
GO:0031167; Biological process: rRNA methylation.
GO:0005737; Cellular component: cytoplasm.


PROSITE PS01153; NOL1_NOP2_SUN; 1;
Pfam PF01189; Nol1_Nop2_Fmu; 1;
PF01029; NusB; 1;
TIGRFAMs TIGR00563; RsmB; 1;


From: RSMB_ECOLI (P36929)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     254     260       S-adenosyl-L-methionine binding (By similarity)     C-[AS]-[AG]-P-G-G-K  
ACT_SITE     375     375       Nucleophile (Potential)     C  
BINDING     277     277       S-adenosyl-L-methionine (By similarity)     D  
BINDING     303     303       S-adenosyl-L-methionine (By similarity)     D  
BINDING     322     322       S-adenosyl-L-methionine (By similarity)     D  


Size range: 422-433 amino acids
Related Rules: None
Template: P36929 (RSMB_ECOLI)
Fusion: None
Comments: The family is restricted to Enterobacteriales in order to avoid wrong matches.


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