HAMAP

Accession	MF_01955
Dates	10-APR-2006 (Created) 19-SEP-2011 (Last updated, Version 14)

Data class

Protein

Predictors

HAMAP; MF_01955; [distribution of match scores in UniProtKB];[seed alignment for MF_01955]

Names

Urease_beta_gamma

Identifier

URE23

Protein name

RecName: Full=Urease subunit alpha; EC=3.5.1.5; AltName: Full=Urea amidohydrolase subunit alpha;

Gene name

ureA

Protein name

RecName: Full=Urease subunit gamma/beta; EC=3.5.1.5; AltName: Full=Urea amidohydrolase subunit gamma/beta;

Gene name

ureAB

CATALYTIC ACTIVITY: Urea + H(2)O = CO(2) + 2 NH(3).

PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1.

SUBUNIT: Heterohexamer of 3 UreA (alpha) and 3 UreB (beta) subunits (By similarity).

SUBUNIT: Heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: In the N-terminal section; belongs to the urease gamma subunit family.

SIMILARITY: In the C-terminal section; belongs to the urease beta subunit family.

CAUTION: The orthologous protein is known as the gamma/beta subunit (UreAB) in most other bacteria.

Pfam	PF00699; Urease_beta; 1; PF00547; Urease_gamma; 1;
TIGRFAMs	TIGR00192; Urease_beta; 1; TIGR00193; Urease_gam; 1;

Cytoplasm, Hydrolase.

GO:0009039; Molecular function: urease activity.
GO:0019627; Biological process: urea metabolic process.
GO:0005737; Cellular component: cytoplasm.

From: URE23_HELPY (P14916)
Key		From		To		Description		Condition		FTGroup
REGION		Nter		102		Urease gamma
REGION		103		Cter		Urease beta

Size range:	219-238 amino acids
Related UniRules:	MF_00739 (URE3); MF_01954 (URE2)
Template:	P14916 (URE23_HELPY)
Scope:	Bacteria; Streptomycineae Bacteria; Deinococcales Bacteria; Campylobacterales Bacteria; Pseudomonadaceae Archaea; Sulfolobales
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None