HAMAP rule MF_00004

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_00004
Accession	MF_00004
Dates	1-JUN-2001 (Created) 14-MAY-2024 (Last updated, Version 32)
Name	Aden_phosphoribosyltr
Scope(s)	Bacteria Archaea
Template(s)	P69503 (APT_ECOLI); [ Recover all ]
Triggered by	HAMAP; MF_00004 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	APT
Protein name	RecName: Full=Adenine phosphoribosyltransferase; Short=APRT; EC=2.4.2.7;
Gene name	Name=apt;

Comments [?]

FUNCTION	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
CATALYTIC ACTIVITY	Reaction=AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine; Xref=Rhea:RHEA:16609, ChEBI:CHEBI:16708, ChEBI:CHEBI:33019, ChEBI:CHEBI:58017, ChEBI:CHEBI:456215; EC=2.4.2.7;
PATHWAY	Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.
SUBUNIT	Homodimer.
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the purine/pyrimidine phosphoribosyltransferase family.

Keywords [?]

Gene Ontology [?]

GO:0003999; Molecular function:adenine phosphoribosyltransferase activity

GO:0044209; Biological process:AMP salvage

GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Features [?]

Additional information [?]