 |
|
| Annotation rule MF_00004 |
General rule information
[?]
| Accession | MF_00004 |
| Dates | 1-JUN-2001 (Created) 20-NOV-2019 (Last updated, Version 30) |
| Name | Aden_phosphoribosyltr |
| Scope | Bacteria
Archaea |
| Template | P69503 (APT_ECOLI) |
| Triggered by |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
| Identifier |
|
| Protein name |
|
||||||||||||
| Gene name |
|
Comments
[?]
| Function | Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. |
| Catalytic activity | RHEA:16609: AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine
EC 2.4.2.7 |
| Pathway | Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1. |
| Subunit | Homodimer. |
| Subcellular location | Cytoplasm. |
| Similarity | Belongs to the purine/pyrimidine phosphoribosyltransferase family. |
Keywords
[?]
Gene Ontology
[?]
GO:0003999; Molecular function: adenine phosphoribosyltransferase activity.
GO:0006168; Biological process: adenine salvage.
GO:0009116; Biological process: nucleoside metabolic process.
GO:0005737; Cellular component: cytoplasm.
GO:0006168; Biological process: adenine salvage.
GO:0009116; Biological process: nucleoside metabolic process.
GO:0005737; Cellular component: cytoplasm.
Cross-references
[?]
Additional information
[?]
| Size range | 150-280 amino acids |
| Related rules | None |
| Fusion | None |