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HAMAP rule MF_00006

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General rule information [?]

Accession MF_00006
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 47)
Name Arg_succ_lyase
Scope(s) Bacteria
Archaea
Template(s) P11447 (ARLY_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00006 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ARLY
Protein name RecName: Full=Argininosuccinate lyase;
                 Short=ASAL;
                 EC=4.3.2.1;
AltName: Full=Arginosuccinase;
Gene name Name=argH;

Comments [?]

CATALYTIC ACTIVITY Reaction=2-(N(omega)-L-arginino)succinate = fumarate + L-arginine; Xref=Rhea:RHEA:24020, ChEBI:CHEBI:29806, ChEBI:CHEBI:32682, ChEBI:CHEBI:57472; EC=4.3.2.1;
PATHWAYAmino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the lyase 1 family. Argininosuccinate lyase subfamily.

Keywords [?]


Gene Ontology [?]

GO:0004056; Molecular function:argininosuccinate lyase activity
GO:0006526; Biological process:arginine biosynthetic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF00206; Lyase_1; 1;
PRINTS PR00145; ARGSUCLYASE; 1;
PRINTS PR00149; FUMRATELYASE; 1;
NCBIfam TIGR00838; argH; 1;
PROSITE PS00163; FUMARATE_LYASES; 1;

Features [?]


Additional information [?]

Size range 360-550 amino acids
Related rules None
Fusion Nter: <ATP-grasp domain> Cter: MF_01105 (argA); <Unknown>



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