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HAMAP rule MF_00006

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General rule information [?]

Accession MF_00006
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 47)
Name Arg_succ_lyase
Scope
Bacteria
Archaea
Template P11447 (ARLY_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ARLY
Protein name
RecName: Full=Argininosuccinate lyase;
Short=ASAL;
EC 4.3.2.1;
AltName: Full=Arginosuccinase;
Gene name
argH

Comments [?]

Catalytic activity RHEA:24020: 2-(N(omega)-L-arginino)succinate = fumarate + L-arginine
EC 4.3.2.1
Pathway Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.
Subcellular location Cytoplasm.
Similarity Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

Keywords [?]


Gene Ontology [?]

GO:0004056; Molecular function: argininosuccinate lyase activity.
GO:0006526; Biological process: arginine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF00206; Lyase_1; 1;
PRINTS PR00145; ARGSUCLYASE; 1;
PR00149; FUMRATELYASE; 1;
NCBIfam TIGR00838; argH; 1;
PROSITE PS00163; FUMARATE_LYASES; 1;

Additional information [?]

Size range 360-550 amino acids
Related rules None
Fusion Nter: <ATP-grasp domain>; Cter: MF_01105 (argA), <Unknown>