HAMAP rule MF_00006
General rule information
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| Accession | MF_00006 |
| Dates | 1-JUN-2001 (Created)
28-NOV-2023 (Last updated, Version 48) |
| Name | Arg_succ_lyase |
| Scope(s) |
Bacteria Archaea |
| Template(s) | P11447 (ARLY_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_00006 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | ARLY |
| Protein name | RecName: Full=Argininosuccinate lyase; Short=ASAL; EC=4.3.2.1; AltName: Full=Arginosuccinase; |
| Gene name | Name=argH; |
Comments
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| CATALYTIC ACTIVITY | Reaction=2-(N(omega)-L-arginino)succinate = fumarate + L-arginine; Xref=Rhea:RHEA:24020, ChEBI:CHEBI:29806, ChEBI:CHEBI:32682, ChEBI:CHEBI:57472; EC=4.3.2.1; |
| PATHWAY | Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. |
Keywords
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Gene Ontology
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| GO:0004056; Molecular function:argininosuccinate lyase activity |
| GO:0006526; Biological process:arginine biosynthetic process |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF00206; Lyase_1; 1; |
| PRINTS | PR00145; ARGSUCLYASE; 1; |
| PRINTS | PR00149; FUMRATELYASE; 1; |
| NCBIfam | TIGR00838; argH; 1; |
| PROSITE | PS00163; FUMARATE_LYASES; 1; |
Features
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Additional information
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| Size range | 360-550 amino acids |
| Related rules |
None |
| Fusion | Nter: <ATP-grasp domain> Cter: MF_01105 (argA); <Unknown> |