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Annotation rule MF_00016
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General rule information [?]

Accession MF_00016
Dates 1-JUN-2001 (Created)
20-NOV-2019 (Last updated, Version 30)
Name DNA_helic_RuvB
Scope
Bacteria
Archaea; Methanomicrobiales
Templates P0A812 (RUVB_ECOLI); Q5SL87 (RUVB_THET8): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
RUVB
Protein name
RecName: Full=Holliday junction ATP-dependent DNA helicase RuvB;
EC 3.6.4.12;
Gene name
ruvB

Comments [?]

Function The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
Catalytic activity RHEA:13065: ATP + H2O = ADP + H(+) + phosphate
EC 3.6.4.12
Subunit Forms a complex with RuvA.
Similarity Belongs to the RuvB family.

Keywords [?]


Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0009378; Molecular function: four-way junction helicase activity.
GO:0006310; Biological process: DNA recombination.
GO:0006281; Biological process: DNA repair.
GO:0009432; Biological process: SOS response.

Cross-references [?]

Pfam PF00004; AAA; 1;
TIGRFAMs TIGR00635; RuvB; 1;

Features [?]

From: RUVB_ECOLI (P0A812)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     62     69       ATP     G-x-x-G-x-G-K-T  

Additional information [?]

Size range 290-415 amino acids
Related rules None
Fusion None