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HAMAP rule MF_00024

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General rule information [?]

Accession MF_00024
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 33)
Name CobD_CbiB
Scope
Bacteria
Archaea
Template Q05600 (CBIB_SALTY)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

case <OC:Salmonella>
Identifier
CBIB
else
Identifier
COBD
end case
case <OC:Salmonella>
Protein name
RecName: Full=Cobalamin biosynthesis protein CbiB;
else case <OC:Bacteria> and not <OC:Salmonella>
Protein name
RecName: Full=Cobalamin biosynthesis protein CobD;
else case <OC:Archaea>
Protein name
RecName: Full=Probable cobalamin biosynthesis protein CobD;
end case
case <OC:Salmonella>
Gene name
cbiB
else
Gene name
cobD
end case

Comments [?]

case <OC:Salmonella>
Function Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. However, the true cosubstrate could be (R)-1-amino-2-propanol O-2-phosphate, leading to cobinamide phosphate.
else
Function Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
end case
Pathway Cofactor biosynthesis; adenosylcobalamin biosynthesis.
Subcellular location Cell membrane; Multi-pass membrane protein.
Similarity Belongs to the CobD/CbiB family.

Keywords [?]

Cell membrane
Cobalamin biosynthesis
Membrane
Transmembrane
Transmembrane helix

Gene Ontology [?]

GO:0015420; Molecular function: ABC-type vitamin B12 transporter activity.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

NCBIfam TIGR00380; CobD; 1;

Computed features [?]

General Transmembrane; -; 5-6; trigger=yes;

Additional information [?]

Size range 283-342 amino acids
Related rules None
Fusion None
Comments Called cbiB in Salmonella


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