HAMAP rule MF_00024

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_00024
Accession	MF_00024
Dates	28-FEB-2005 (Created) 01-MAR-2024 (Last updated, Version 27)
Name	CobD_CbiB
Scope(s)	Bacteria Archaea
Template(s)	Q05600; [ Recover all ]
Triggered by	HAMAP; MF_00024 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

case <OC:Salmonella>
Identifier	CBIB
else
Identifier	COBD
end case
case <OC:Salmonella>
Protein name	RecName: Full=Cobalamin biosynthesis protein CbiB;
else case <OC:Bacteria> and not <OC:Salmonella>
Protein name	RecName: Full=Cobalamin biosynthesis protein CobD;
else case <OC:Archaea>
Protein name	RecName: Full=Probable cobalamin biosynthesis protein CobD;
end case
case <OC:Salmonella>
Gene name	Name=cbiB;
else
Gene name	Name=cobD;
end case

Comments [?]

case <OC:Salmonella>
FUNCTION	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. However, the true cosubstrate could be (R)-1-amino-2-propanol O-2-phosphate, leading to cobinamide phosphate.
else
FUNCTION	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
end case
PATHWAY	Cofactor biosynthesis; adenosylcobalamin biosynthesis.
SUBCELLULAR LOCATION	Cell membrane; Multi-pass membrane protein.
SIMILARITY	Belongs to the CobD/CbiB family.

Keywords [?]

Gene Ontology [?]

GO:0015420; Molecular function:ABC-type vitamin B12 transporter activity

GO:0005886; Cellular component:plasma membrane

GO:0009236; Biological process:cobalamin biosynthetic process

Cross-references [?]

NCBIfam	TIGR00380; CobD; 1;
General	Transmembrane; -; 5-6;

Features [?]

Additional information [?]