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HAMAP rule MF_00024

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General rule information [?]

Accession MF_00024
Dates 1-JUN-2001 (Created)
1-MAR-2024 (Last updated, Version 34)
Name CobD_CbiB
Scope(s) Bacteria
Archaea
Template(s) Q05600 (CBIB_SALTY); [ Recover all ]
Triggered by HAMAP; MF_00024 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

case <OC:Salmonella>
Identifier CBIB
else
Identifier COBD
end case
case <OC:Salmonella>
Protein name RecName: Full=Cobalamin biosynthesis protein CbiB;
else case <OC:Bacteria> and not <OC:Salmonella>
Protein name RecName: Full=Cobalamin biosynthesis protein CobD;
else case <OC:Archaea>
Protein name RecName: Full=Probable cobalamin biosynthesis protein CobD;
end case
case <OC:Salmonella>
Gene name Name=cbiB;
else
Gene name Name=cobD;
end case

Comments [?]

case <OC:Salmonella>
FUNCTIONConverts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. However, the true cosubstrate could be (R)-1-amino-2-propanol O-2-phosphate, leading to cobinamide phosphate.
else
FUNCTIONConverts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
end case
PATHWAYCofactor biosynthesis; adenosylcobalamin biosynthesis.
SUBCELLULAR LOCATIONCell membrane; Multi-pass membrane protein.
SIMILARITYBelongs to the CobD/CbiB family.

Keywords [?]


Gene Ontology [?]

GO:0015420; Molecular function:ABC-type vitamin B12 transporter activity
GO:0005886; Cellular component:plasma membrane
GO:0009236; Biological process:cobalamin biosynthetic process

Cross-references [?]

NCBIfam TIGR00380; CobD; 1;
General Transmembrane; -; 5-6;

Features [?]


Additional information [?]

Size range 283-342 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments Called cbiB in Salmonella



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