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Annotation rule MF_00042 |
Accession | MF_00042 |
Dates | 1-JUN-2001 (Created) 20-NOV-2019 (Last updated, Version 33) |
Name | RNase_H |
Scope | Bacteria |
Templates | P0A7Y4 (RNH_ECOLI); P29253 (RNH_THET8): [Recover all] |
Triggered by |
Identifier |
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Protein name |
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Gene name |
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Function | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. |
Catalytic activity | Reaction=Endonucleolytic cleavage to 5'-phosphomonoester.; EC=3.1.26.4; |
Cofactor | Mg(2+) Note: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding. |
Subunit | Monomer. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the RNase H family. |
From: RNH_ECOLI (P0A7Y4) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
METAL | 10 | 10 | Magnesium 1 | D | ||||||||
METAL | 10 | 10 | Magnesium 2 | D | ||||||||
METAL | 48 | 48 | Magnesium 1 | E | ||||||||
METAL | 70 | 70 | Magnesium 1 | D | ||||||||
METAL | 134 | 134 | Magnesium 2 | D |
Size range | 143-231 amino acids |
Related rules | None |
Fusion | None |
Comments | Possible C-terminal domain in STRCO. Divergence in TREPA. |