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Annotation rule MF_00052 |
Accession | MF_00052 |
Dates | 1-JUN-2001 (Created) 20-NOV-2019 (Last updated, Version 30) |
Name | RNase_HII |
Scope | Bacteria
Archaea |
Templates | O31744 (RNH2_BACSU); P10442 (RNH2_ECOLI); O29634 (RNH2_ARCFU); Q57599 (RNH2_METJA); O74035 (RNH2_THEKO): [Recover all] |
Triggered by |
Triggered by |
Identifier |
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Protein name |
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Gene name |
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Function | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. |
Catalytic activity | Reaction=Endonucleolytic cleavage to 5'-phosphomonoester.; EC=3.1.26.4; |
Cofactor | Mn(2+) Mg(2+) Note: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the RNase HII family. |
From: RNH2_ECOLI (P10442) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
METAL | 16 | 16 | Divalent metal cation | D | ||||||||
METAL | 17 | 17 | Divalent metal cation | E | ||||||||
METAL | 108 | 108 | Divalent metal cation | D |
From: RNH2_METJA (Q57599) | ||||||||||||
METAL | 7 | 7 | Divalent metal cation | D | ||||||||
METAL | 8 | 8 | Divalent metal cation | E | ||||||||
METAL | 112 | 112 | Divalent metal cation | D |
Size range | 181-315 amino acids |
Size range | 195-277 amino acids |
Related rules | None |
Fusion | None |
Comments | Divergent CAUVC not shown in alignment. Possible wrong start in a number of cases. |