HAMAP logo

HAMAP rule MF_00056

Send feedback

General rule information [?]

Accession MF_00056
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 33)
Name KDO8P_synth
Scope(s) Bacteria
Template(s) P0A715 (KDSA_ECOLI); O66496 (KDSA_AQUAE); [ Recover all ]
Triggered by HAMAP; MF_00056 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier KDSA
Protein name RecName: Full=2-dehydro-3-deoxyphosphooctonate aldolase;
AltName: Full=3-deoxy-D-manno-octulosonic acid 8-phosphate synthase;
AltName: Full=KDO-8-phosphate synthase;
                 Short=KDO 8-P synthase;
AltName: Full=Phospho-2-dehydro-3-deoxyoctonate aldolase;
Gene name Name=kdsA;

Comments [?]

CATALYTIC ACTIVITY Reaction=D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 3-deoxy- alpha-D-manno-2-octulosonate-8-phosphate + phosphate; Xref=Rhea:RHEA:14053, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:57693, ChEBI:CHEBI:58702, ChEBI:CHEBI:85985; EC=;
PATHWAYCarbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3.
case defined <Property:Membrane> and <Property:Membrane=2>
PATHWAYBacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.
end case
SIMILARITYBelongs to the KdsA family.

Keywords [?]

Gene Ontology [?]

GO:0008676; Molecular function:3-deoxy-8-phosphooctulonate synthase activity
GO:0009103; Biological process:lipopolysaccharide biosynthetic process
GO:0019294; Biological process:keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF00793; DAHP_synth_1; 1;
NCBIfam TIGR01362; KDO8P_synth; 1;

Features [?]

Additional information [?]

Size range 263-290 amino acids
Related rules None
Fusion Nter: None Cter: None

View rule in raw text format (no links)