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Annotation rule MF_00056
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General rule information [?]

Accession MF_00056
Dates 1-JUN-2001 (Created)
20-NOV-2019 (Last updated, Version 32)
Name KDO8P_synth
Scope
Bacteria
Templates P0A715 (KDSA_ECOLI); O66496 (KDSA_AQUAE): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
KDSA
Protein name
RecName: Full=2-dehydro-3-deoxyphosphooctonate aldolase;
EC 2.5.1.55;
AltName: Full=3-deoxy-D-manno-octulosonic acid 8-phosphate synthase;
AltName: Full=KDO-8-phosphate synthase;
Short=KDO 8-P synthase;
Short=KDOPS;
AltName: Full=Phospho-2-dehydro-3-deoxyoctonate aldolase;
Gene name
kdsA

Comments [?]

Catalytic activity RHEA:14053: D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + phosphate
EC 2.5.1.55
Pathway Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3.
case defined <Property:Membrane> and <Property:Membrane=2>
Pathway Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.
end case
Subcellular location Cytoplasm.
Similarity Belongs to the KdsA family.

Keywords [?]

Cytoplasm
Lipopolysaccharide biosynthesis
Transferase

Gene Ontology [?]

GO:0008676; Molecular function: 3-deoxy-8-phosphooctulonate synthase activity.
GO:0009103; Biological process: lipopolysaccharide biosynthetic process.
GO:0019294; Biological process: keto-3-deoxy-D-manno-octulosonic acid biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF00793; DAHP_synth_1; 1;
TIGRFAMs TIGR01362; KDO8P_synth; 1;

Additional information [?]

Size range 263-290 amino acids
Related rules None
Fusion None


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