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Annotation rule MF_00058 |
General rule information
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Accession |
MF_00058 |
Dates |
1-JUN-2001 (Created) 20-NOV-2019 (Last updated, Version 21) |
Propagated annotation
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Identifier, protein and gene names
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Protein name |
RecName:
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Full=F420-dependent methylenetetrahydromethanopterin dehydrogenase;
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Short=MTD;
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EC 1.5.98.1;
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AltName:
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Full=Coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase;
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case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
Function |
Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. |
else
Function |
Catalyzes the oxidation of methylene-H(4)MPT to methenyl-H(4)MPT(+). |
end case
Catalytic activity |
RHEA:16721: 5,10-methylenetetrahydromethanopterin + 2 H(+) + oxidized coenzyme F420-(gamma-Glu)(n) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420-(gamma-Glu)(n)
EC 1.5.98.1
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case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
Pathway |
One-carbon metabolism; methanogenesis from CO(2); 5,10-methylene-5,6,7,8-tetrahydromethanopterin from 5,10-methenyl-5,6,7,8-tetrahydromethanopterin (coenzyme F420 route): step 1/1. |
end case
case <OC:Archaeoglobales>
Pathway |
Metabolic intermediate metabolism; lactate oxidation. |
end case
Similarity |
Belongs to the MTD family. |
case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
end case
GO:0030268; Molecular function: methylenetetrahydromethanopterin dehydrogenase activity.
GO:0006730; Biological process: one-carbon metabolic process.
case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
end case
Additional information
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Size range |
273-283 amino acids |
Related rules |
None |
Fusion |
None |