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HAMAP rule MF_00065

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General rule information [?]

Accession MF_00065
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 36)
Name Adenylyl_sulf_kinase
Scope(s) Bacteria
Template(s) P0A6J1 (CYSC_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00065 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier CYSC
Protein name RecName: Full=Adenylyl-sulfate kinase;
AltName: Full=APS kinase;
AltName: Full=ATP adenosine-5'-phosphosulfate 3'-phosphotransferase;
AltName: Full=Adenosine-5'-phosphosulfate kinase;
Gene name Name=cysC;

Comments [?]

FUNCTIONCatalyzes the synthesis of activated sulfate.
CATALYTIC ACTIVITY Reaction=adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H(+); Xref=Rhea:RHEA:24152, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:58243, ChEBI:CHEBI:58339, ChEBI:CHEBI:456216; EC=;
PATHWAYSulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 2/3.
SIMILARITYBelongs to the APS kinase family.

Keywords [?]

Gene Ontology [?]

GO:0004020; Molecular function:adenylylsulfate kinase activity
GO:0005524; Molecular function:ATP binding
GO:0000103; Biological process:sulfate assimilation

Cross-references [?]

Pfam PF01583; APS_kinase; 1;
NCBIfam TIGR00455; ApsK; 1;

Features [?]

Key From To Description Tag Condition FTGroup
BINDING 35 42 /ligand="ATP"
ACT_SITE 109 109 /note="Phosphoserine intermediate" S

Additional information [?]

Size range 155-214 amino acids
Related rules None
Fusion Nter: MF_00062 (cysN); MF_00066 (sat) Cter: None
Comments Problematic entry

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