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HAMAP rule MF_00065

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General rule information [?]

Accession MF_00065
Dates 1-JUN-2001 (Created)
19-NOV-2022 (Last updated, Version 35)
Name Adenylyl_sulf_kinase
Scope
Bacteria
Archaea
Template P0A6J1 (CYSC_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
CYSC
Protein name
RecName: Full=Adenylyl-sulfate kinase;
EC 2.7.1.25;
AltName: Full=APS kinase;
AltName: Full=ATP adenosine-5'-phosphosulfate 3'-phosphotransferase;
AltName: Full=Adenosine-5'-phosphosulfate kinase;
Gene name
cysC

Comments [?]

Function Catalyzes the synthesis of activated sulfate.
Catalytic activity RHEA:24152: adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H(+)
EC 2.7.1.25
Pathway Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 2/3.
Similarity Belongs to the APS kinase family.

Keywords [?]

Transferase
Kinase
ATP-binding
Nucleotide-binding
Phosphoprotein

Gene Ontology [?]

GO:0004020; Molecular function: adenylylsulfate kinase activity.
GO:0005524; Molecular function: ATP binding.
GO:0000103; Biological process: sulfate assimilation.

Cross-references [?]

Pfam PF01583; APS_kinase; 1;
TIGRFAMs TIGR00455; ApsK; 1;

Features [?]

From: CYSC_ECOLI (P0A6J1)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     35     42       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     G-x(4)-G-K-[ST]  
ACT_SITE     109     109       Phosphoserine intermediate     S  

Additional information [?]

Size range 155-214 amino acids
Related rules None
Fusion Nter: MF_00062 (cysN), MF_00066 (sat); Cter: None
Comments Problematic entry


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