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HAMAP rule MF_00074

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General rule information [?]

Accession MF_00074
Dates 1-JUN-2001 (Created)
26-JAN-2023 (Last updated, Version 34)
Name 16SrRNA_methyltr_G
Scope
Bacteria
Templates P0A6U5 (RSMG_ECOLI); P25813 (RSMG_BACSU); P9WGW9 (RSMG_MYCTU); O54571 (RSMG_STRCO): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
RSMG
case <OC:Pseudomonadota>
Protein name
RecName: Full=Ribosomal RNA small subunit methyltransferase G;
EC 2.1.1.170;
AltName: Full=16S rRNA 7-methylguanosine methyltransferase;
Short=16S rRNA m7G methyltransferase;
else
Protein name
RecName: Full=Ribosomal RNA small subunit methyltransferase G;
EC 2.1.1.-;
AltName: Full=16S rRNA 7-methylguanosine methyltransferase;
Short=16S rRNA m7G methyltransferase;
end case
Gene name
rsmG

Comments [?]

case <OC:Pseudomonadota>
Function Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
Catalytic activity RHEA:42732: guanosine(527) in 16S rRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(527) in 16S rRNA + S-adenosyl-L-homocysteine
EC 2.1.1.170
else case <OC:Bacillales>
Function Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
else case <OC:Actinomycetales>
Function Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.
else
Function Specifically methylates the N7 position of a guanine in 16S rRNA.
end case
Subcellular location Cytoplasm.
Similarity Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.

Keywords [?]

Cytoplasm
Methyltransferase
rRNA processing
S-adenosyl-L-methionine
Transferase

Gene Ontology [?]

GO:0070043; Molecular function: rRNA (guanine-N7-)-methyltransferase activity.
GO:0006364; Biological process: rRNA processing.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF02527; GidB; 1;
PIRSF PIRSF003078; GidB; 1;
TIGRFAMs TIGR00138; GidB; 1;

Features [?]

From: RSMG_THET8 (Q9LCY2)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING (Optional)     111     113       /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789     [DE]-x-[TS]  
BINDING (Optional)     139     140       /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789     [AGVILSC]-[EYQ]  
BINDING     88     88       /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789     G  
BINDING (Optional)     93     93       /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789     [FLYMQ]  
BINDING     158     158       /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789     [RQK]  

Additional information [?]

Size range 178-288 amino acids
Related rules None
Fusion Nter: None; Cter: <SpoU_methylase>


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