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Annotation rule MF_00075 |
General rule information
[?]
Accession |
MF_00075 |
Dates |
1-JUN-2001 (Created) 20-NOV-2019 (Last updated, Version 43) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
case not <OG:Chloroplast>
Protein name |
RecName:
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Full=Translation initiation factor IF-1;
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end case
case <OG:Chloroplast>
Protein name |
RecName:
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Full=Translation initiation factor IF-1, chloroplastic;
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end case
Function |
One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. |
Subunit |
Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly. |
case not <OG:Chloroplast>
Subcellular location |
Cytoplasm. |
end case
case <OG:Chloroplast>
Subcellular location |
Plastid, chloroplast. |
end case
Similarity |
Belongs to the IF-1 family. |
case not <OG:Chloroplast>
end case
case <OC:Bacillaceae> and <FT:1>
end case
GO:0019843; Molecular function: rRNA binding.
GO:0003743; Molecular function: translation initiation factor activity.
GO:0006413; Biological process: translational initiation.
GO:0043022; Molecular function: ribosome binding.
case not <OG:Chloroplast>
end case
case <OG:Chloroplast>
end case
case <OC:Bacillaceae>
From: IF1_BACSU (P20458) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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MOD_RES
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60
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60
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Phosphotyrosine
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Y
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end case
Additional information
[?]
Size range |
70-113 amino acids |
Related rules |
None |
Fusion |
None |
Comments |
Possible wrong start in MYCSP Pseudogene in the plastid genome in most rosids (including ARATH), and Solanaceae (including TOBAC). MEDLINE=21149877; PubMed=11251102; DOI=10.1105/tpc.13.3.645; Millen R.S., Olmstead R.G., Adams K.L., Palmer J.D., Lao N.T., Heggie L., Kavanagh T.A., Hibberd J.M., Gray J.C., Morden C.W., Calie P.J., Jermiin L.S., Wolfe K.H.; "Many parallel losses of infA from chloroplast DNA during angiosperm evolution with multiple independent transfers to the nucleus."; Plant Cell 13:645-658(2001). |