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Annotation rule MF_00077
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General rule information [?]

Accession MF_00077
Dates 1-JUN-2001 (Created)
20-NOV-2019 (Last updated, Version 29)
Name tRNA_methyltr_aTrm56
Templates O58214 (TRM56_PYRHO); Q9UYD1 (TRM56_PYRAB); O29507 (TRM56_ARCFU): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=tRNA (cytidine(56)-2'-O)-methyltransferase;
AltName: Full=tRNA ribose 2'-O-methyltransferase aTrm56;

Comments [?]

Function Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.
Catalytic activity RHEA:42968: cytidine(56) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(56) in tRNA + H(+) + S-adenosyl-L-homocysteine
Subunit Homodimer.
Subcellular location Cytoplasm.
Similarity Belongs to the aTrm56 family.

Keywords [?]

Gene Ontology [?]

GO:0008175; Molecular function: tRNA methyltransferase activity.
GO:0002128; Biological process: tRNA nucleoside ribose methylation.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01994; Trm56; 1;
PF01966; HD; 0-1;
TIGRFAMs TIGR00277; HDIG; 0-1;
PROSITE PS51831; HD; 0-1; trigger=PRU01175;

Features [?]

From: TRM56_PYRHO (O58214)
Key     From     To       Description   Tag   Condition   FTGroup
REGION (Optional)     109     113       S-adenosyl-L-methionine binding     G-[GAS]-[ED]-[KR]-V  
REGION (Optional)     127     134       S-adenosyl-L-methionine binding     [VI]-[GAS]-N-Q-P-H-S-E  
BINDING     80     80       S-adenosyl-L-methionine; via carbonyl oxygen     L  

Additional information [?]

Size range 168-218 amino acids
Related rules None
Fusion Nter: None; Cter: <HD domain>
Comments Shorter N-terminus in SULAC and SACS2.