HAMAP rule MF_00083

General rule information [?]

Accession	MF_00083
Dates	1-JUN-2001 (Created) 6-JAN-2022 (Last updated, Version 23)

Name	Pept_tRNA_hydro_bact

Scope

Bacteria

Templates

P0A7D1 (PTH_ECOLI); Q6YP15 (PTH_STAAU): [Recover all]

Triggered by

HAMAP; MF_00083 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

PTH

Protein name

RecName:		Full=Peptidyl-tRNA hydrolase;
		Short=PTH;
		EC 3.1.1.29;

Gene name

pth

Comments [?]

Function	The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
Catalytic activity	RHEA:54448: an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+) EC 3.1.1.29
Subunit	Monomer.
Subcellular location	Cytoplasm.
Similarity	Belongs to the PTH family.

Keywords [?]

Cytoplasm
Hydrolase

Gene Ontology [?]

GO:0004045; Molecular function: aminoacyl-tRNA hydrolase activity.
GO:0006412; Biological process: translation.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam	PF01195; Pept_tRNA_hydro; 1;
TIGRFAMs	TIGR00447; Pth; 1;
PROSITE	PS01195; PEPT_TRNA_HYDROL_1; 1;
	PS01196; PEPT_TRNA_HYDROL_2; 1;

Additional information [?]

Size range	172-250 amino acids
Related rules	None
Fusion	None
Comments	Called spoVC in BACSU

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