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HAMAP rule MF_00083

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General rule information [?]

Accession MF_00083
Dates 1-JUN-2001 (Created)
6-JAN-2022 (Last updated, Version 23)
Name Pept_tRNA_hydro_bact
Scope
Bacteria
Templates P0A7D1 (PTH_ECOLI); Q6YP15 (PTH_STAAU): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
PTH
Protein name
RecName: Full=Peptidyl-tRNA hydrolase;
Short=PTH;
EC 3.1.1.29;
Gene name
pth

Comments [?]

Function The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
Catalytic activity RHEA:54448: an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)
EC 3.1.1.29
Subunit Monomer.
Subcellular location Cytoplasm.
Similarity Belongs to the PTH family.

Keywords [?]


Gene Ontology [?]

GO:0004045; Molecular function: aminoacyl-tRNA hydrolase activity.
GO:0006412; Biological process: translation.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01195; Pept_tRNA_hydro; 1;
TIGRFAMs TIGR00447; Pth; 1;
PROSITE PS01195; PEPT_TRNA_HYDROL_1; 1;
PS01196; PEPT_TRNA_HYDROL_2; 1;

Additional information [?]

Size range 172-250 amino acids
Related rules None
Fusion None
Comments Called spoVC in BACSU