HAMAP rule MF_00091
General rule information
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Accession | MF_00091 |
Dates | 1-JUN-2001 (Created) 19-NOV-2022 (Last updated, Version 28) |
Name | LuxS |
Scope | Bacteria |
Templates | O34667 (LUXS_BACSU); Q9PN97 (LUXS_CAMJE); Q9RRU8 (LUXS_DEIRA); P45578 (LUXS_ECOLI); P44007 (LUXS_HAEIN): [Recover all] |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). |
Catalytic activity | RHEA:17753: S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3-dione + L-homocysteine
EC 4.4.1.21 |
case <FTGroup:1>
Cofactor | Fe cation Note: Binds 1 Fe cation per subunit. |
end case
Subunit | Homodimer. |
Similarity | Belongs to the LuxS family. |
Keywords
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case <FTGroup:1>
end case
Gene Ontology
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GO:0043768; Molecular function: S-ribosylhomocysteine lyase activity.
GO:0009372; Biological process: quorum sensing.
GO:0009372; Biological process: quorum sensing.
Cross-references
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Features
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From: LUXS_BACSU (O34667) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 54 | 54 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875 | H | 1 | |||||||
BINDING | 58 | 58 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875 | H | 1 | |||||||
BINDING | 126 | 126 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875 | C | 1 |
Additional information
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Size range | 151-173 amino acids |
Related rules | None |
Fusion | None |