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Annotation rule MF_00091 |
Accession | MF_00091 |
Dates | 1-JUN-2001 (Created) 20-NOV-2019 (Last updated, Version 26) |
Name | LuxS |
Scope | Bacteria |
Templates | O34667 (LUXS_BACSU); Q9PN97 (LUXS_CAMJE); Q9RRU8 (LUXS_DEIRA); P45578 (LUXS_ECOLI); P44007 (LUXS_HAEIN): [Recover all] |
Triggered by |
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Protein name |
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Gene name |
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Function | Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). |
Catalytic activity | RHEA:17753: S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3-dione + L-homocysteine
EC 4.4.1.21 |
Cofactor | Fe cation Note: Binds 1 Fe cation per subunit. |
Subunit | Homodimer. |
Similarity | Belongs to the LuxS family. |
From: LUXS_BACSU (O34667) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
METAL | 54 | 54 | Iron | H | 1 | |||||||
METAL | 58 | 58 | Iron | H | 1 | |||||||
METAL | 126 | 126 | Iron | C | 1 |
Size range | 151-173 amino acids |
Related rules | None |
Fusion | None |