HAMAP rule MF_00092
General rule information
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| Accession | MF_00092 |
| Dates | 1-JUN-2001 (Created) 19-NOV-2022 (Last updated, Version 27) |
| Name | MutS2 |
| Scope | Bacteria |
| Templates | Q5SHT5 (MUTS2_THET8); O25338 (MUTS2_HELPY); Q9X105 (MUTS2_THEMA): [Recover all] |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity. |
| Subunit | Homodimer. |
| Similarity | Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. |
Keywords
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Gene Ontology
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GO:0005524; Molecular function: ATP binding.
GO:0003677; Molecular function: DNA binding.
GO:0004519; Molecular function: endonuclease activity.
GO:0003677; Molecular function: DNA binding.
GO:0004519; Molecular function: endonuclease activity.
Cross-references
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| Pfam | PF00488; MutS_V; 1; |
| PF01713; Smr; 1; | |
| PIRSF | PIRSF005814; MutS_YshD; 1; |
| TIGRFAMs | TIGR01069; MutS2; 1; |
| PROSITE | PS00486; DNA_MISMATCH_REPAIR_2; 1; |
| PS50828; SMR; 1; trigger=PRU00321; |
Features
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| From: MUTS2_THET8 (Q5SHT5) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 315 | 322 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 | G-x-N-x-G-G-K-[TS] | ||||||||
Additional information
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| Size range | 660-920 amino acids |
| Related rules | None |
| Fusion | None |