HAMAP rule MF_00092
General rule information
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| Accession | MF_00092 |
| Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 28) |
| Name | MutS2 |
| Scope(s) |
Bacteria |
| Template(s) | Q5SHT5 (MUTS2_THET8); O25338 (MUTS2_HELPY); Q9X105 (MUTS2_THEMA); [ Recover all ] |
| Triggered by |
HAMAP; MF_00092 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | MUTS2 |
| Protein name | RecName: Full=Endonuclease MutS2; EC=3.1.-.-; |
| Gene name | Name=mutS2; |
Comments
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| FUNCTION | Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity. |
| SUBUNIT | Homodimer. |
| SIMILARITY | Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. |
Keywords
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Gene Ontology
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| GO:0005524; Molecular function:ATP binding |
| GO:0003677; Molecular function:DNA binding |
| GO:0004519; Molecular function:endonuclease activity |
Cross-references
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| Pfam | PF00488; MutS_V; 1; |
| Pfam | PF01713; Smr; 1; |
| PIRSF | PIRSF005814; MutS_YshD; 1; |
| NCBIfam | TIGR01069; MutS2; 1; |
| PROSITE | PS00486; DNA_MISMATCH_REPAIR_2; 1; |
| PROSITE | PS50828; SMR; 1; |
Features
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| From: MUTS2_THET8 (Q5SHT5) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 315 | 322 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
G-x-N-x-G-G-K-[TS] | ||||||||
Additional information
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| Size range | 660-920 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |