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Annotation rule MF_00101
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General rule information [?]

Accession MF_00101
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 35)
Name AcpS
Scope
Bacteria
Templates P96618 (ACPS_BACSU); P24224 (ACPS_ECOLI); P0A2W6 (ACPS_STRPN): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ACPS
Protein name
RecName: Full=Holo-[acyl-carrier-protein] synthase;
Short=Holo-ACP synthase;
EC 2.7.8.7;
AltName: Full=4'-phosphopantetheinyl transferase AcpS;
Gene name
acpS

Comments [?]

Function Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
Catalytic activity RHEA:12068: apo-[ACP] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo-[ACP]
EC 2.7.8.7
case <FT:1> or <FT:2>
Cofactor Mg(2+)
end case
Subcellular location Cytoplasm.
Similarity Belongs to the P-Pant transferase superfamily. AcpS family.

Keywords [?]

Cytoplasm
Fatty acid biosynthesis
Fatty acid metabolism
Lipid biosynthesis
Lipid metabolism
case <FT:1> or <FT:2>
Magnesium
Metal-binding
end case
Transferase

Gene Ontology [?]

GO:0008897; Molecular function: holo-[acyl-carrier-protein] synthase activity.
case <FT:1> or <FT:2>
GO:0000287; Molecular function: magnesium ion binding.
end case
GO:0006633; Biological process: fatty acid biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01648; ACPS; 1;
TIGRFAMs TIGR00516; AcpS; 1;
TIGR00556; Pantethn_trn; 1;

Features [?]

From: ACPS_ECOLI (P24224)
Key     From     To       Description   Tag   Condition   FTGroup
METAL     9     9       Magnesium     [DE]  
METAL     58     58       Magnesium     [EQ]  

Additional information [?]

Size range 108-157 amino acids
Related rules None
Fusion None
Comments Possible wrong C-terminal sequence in THEMA; not shown in alignment and not used in size range


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