HAMAP rule MF_00115
General rule information
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Accession | MF_00115 |
Dates | 1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 48) |
Name | MscL |
Scope | Bacteria |
Templates | P0A742 (MSCL_ECOLI); P9WJN5 (MSCL_MYCTU); P68806 (MSCL_STAAW); P94585 (MSCL_BACSU); O68284 (MSCL_PECCA); P44789 (MSCL_HAEIN); P68805 (MSCL_STAA8): [Recover all] |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. |
Subunit | Homopentamer. |
case <OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)
Subcellular location | Cell inner membrane; Multi-pass membrane protein. |
else
Subcellular location | Cell membrane; Multi-pass membrane protein. |
end case
Similarity | Belongs to the MscL family. |
Keywords
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case <OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)
end case
Gene Ontology
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GO:0008381; Molecular function: mechanosensitive monoatomic ion channel activity.
GO:0034220; Biological process: monoatomic ion transmembrane transport.
GO:0005886; Cellular component: plasma membrane.
GO:0034220; Biological process: monoatomic ion transmembrane transport.
GO:0005886; Cellular component: plasma membrane.
Cross-references
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Computed features
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General | Transmembrane; -; 2-3; trigger=yes; |
Additional information
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Size range | 100-220 amino acids |
Related rules | None |
Fusion | None |
Comments | None. |