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Annotation rule MF_00115 |
General rule information
[?]
Accession |
MF_00115 |
Dates |
1-JUN-2001 (Created) 25-AUG-2020 (Last updated, Version 44) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Protein name |
RecName:
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Full=Large-conductance mechanosensitive channel;
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Function |
Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. |
Subunit |
Homopentamer. |
case <OC:Proteobacteria> or (defined <Property:Membrane> and <Property:Membrane=2>)
Subcellular location |
Cell inner membrane; Multi-pass membrane protein. |
else
Subcellular location |
Cell membrane; Multi-pass membrane protein. |
end case
Similarity |
Belongs to the MscL family. |
case <OC:Proteobacteria> or (defined <Property:Membrane> and <Property:Membrane=2>)
end case
GO:0008381; Molecular function: mechanosensitive ion channel activity.
GO:0034220; Biological process: ion transmembrane transport.
GO:0005887; Cellular component: integral component of plasma membrane.
General |
Transmembrane; -; 2-3; trigger=yes; |
Additional information
[?]
Size range |
100-220 amino acids |
Related rules |
None |
Fusion |
None |
Comments |
None. |