HAMAP rule MF_00120
General rule information
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Accession | MF_00120 |
Dates | 1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 21) |
Name | GatA |
Scope | Bacteria
Archaea |
Templates | O06491 (GATA_BACSU); Q9LCX3 (GATA_THET8): [Recover all] |
case <OC:Bacteria> or <OC:Archaea>
Triggered by |
end case
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). |
Catalytic activity | RHEA:17521: ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate
EC 6.3.5.7 |
Subunit | Heterotrimer of A, B and C subunits. |
Similarity | Belongs to the amidase family. GatA subfamily. |
Keywords
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Gene Ontology
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GO:0050567; Molecular function: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity.
GO:0006412; Biological process: translation.
GO:0006412; Biological process: translation.
Cross-references
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Features
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From: GATA_BACSU (O06491) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 79 | 79 | Charge relay system | K | ||||||||
ACT_SITE | 154 | 154 | Charge relay system | S | ||||||||
ACT_SITE | 178 | 178 | Acyl-ester intermediate | S |
Additional information
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Size range | 423-524 amino acids |
Related rules | None |
Fusion | None |
Comments | There is a possible divergent gatA in ARCFU: AF1954 |