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HAMAP rule MF_00120

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General rule information [?]

Accession MF_00120
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 21)
Name GatA
Scope(s) Bacteria
Template(s) O06491 (GATA_BACSU); Q9LCX3 (GATA_THET8); [ Recover all ]
Triggered by
case c? <OC:Bacteria> or <OC:Archaea>
HAMAP; MF_00120 (Get profile general information and statistics)
end case

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier GATA
Protein name RecName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit A;
                 Short=Glu-ADT subunit A;
Gene name Name=gatA;

Comments [?]

FUNCTIONAllows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
CATALYTIC ACTIVITY Reaction=ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate; Xref=Rhea:RHEA:17521, Rhea:RHEA-COMP:9681, Rhea:RHEA-COMP:9684, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29985, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:58359, ChEBI:CHEBI:78520, ChEBI:CHEBI:78521, ChEBI:CHEBI:456216; EC=;
SUBUNITHeterotrimer of A, B and C subunits.
SIMILARITYBelongs to the amidase family. GatA subfamily.

Keywords [?]

Gene Ontology [?]

GO:0050567; Molecular function:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
GO:0006412; Biological process:translation

Cross-references [?]

Pfam PF01425; Amidase; 1;
NCBIfam TIGR00132; GatA; 1;

Features [?]

From: GATA_BACSU (O06491)
Key From To Description Tag Condition FTGroup
ACT_SITE 79 79 /note="Charge relay system" K
ACT_SITE 154 154 /note="Charge relay system" S
ACT_SITE 178 178 /note="Acyl-ester intermediate" S

Additional information [?]

Size range 423-524 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments There is a possible divergent gatA in ARCFU: AF1954

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