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HAMAP rule MF_00120

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General rule information [?]

Accession MF_00120
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 21)
Name GatA
Scope
Bacteria
Archaea
Templates O06491 (GATA_BACSU); Q9LCX3 (GATA_THET8): [Recover all]
case <OC:Bacteria> or <OC:Archaea>
end case


Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
GATA
Protein name
RecName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit A;
Short=Glu-ADT subunit A;
EC 6.3.5.7;
Gene name
gatA

Comments [?]

Function Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Catalytic activity RHEA:17521: ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate
EC 6.3.5.7
Subunit Heterotrimer of A, B and C subunits.
Similarity Belongs to the amidase family. GatA subfamily.

Keywords [?]


Gene Ontology [?]

GO:0050567; Molecular function: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity.
GO:0006412; Biological process: translation.

Cross-references [?]

Pfam PF01425; Amidase; 1;
NCBIfam TIGR00132; GatA; 1;
PROSITE PS00571; AMIDASES; 1;

Features [?]

From: GATA_BACSU (O06491)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     79     79       Charge relay system     K  
ACT_SITE     154     154       Charge relay system     S  
ACT_SITE     178     178       Acyl-ester intermediate     S  

Additional information [?]

Size range 423-524 amino acids
Related rules None
Fusion None
Comments There is a possible divergent gatA in ARCFU: AF1954