HAMAP rule MF_00134
General rule information
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| Accession | MF_00134 |
| Dates | 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 33) |
| Name | IGPS |
| Scope(s) |
Bacteria Archaea |
| Template(s) | Q56319 (TRPC_THEMA); P00909 (TRPC_ECOLI); Q06121 (TRPC_SACS2); [ Recover all ] |
| Triggered by |
case c? <OC:Bacteria>
HAMAP; MF_00134_B (Get profile general information and statistics) end case
case c? <OC:Archaea>
HAMAP; MF_00134_A (Get profile general information and statistics) end case
|
Propagated annotation
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Identifier, protein and gene names
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| Identifier | TRPC |
| Protein name | RecName: Full=Indole-3-glycerol phosphate synthase; Short=IGPS; EC=4.1.1.48; |
| Gene name | Name=trpC; |
Comments
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| CATALYTIC ACTIVITY | Reaction=1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O; Xref=Rhea:RHEA:23476, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:58613, ChEBI:CHEBI:58866; EC=4.1.1.48; |
| PATHWAY | Amino-acid biosynthesis; L-tryptophan biosynthesis; L- tryptophan from chorismate: step 4/5. |
| SIMILARITY | Belongs to the TrpC family. |
Keywords
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| Amino-acid biosynthesis |
| Aromatic amino acid biosynthesis |
| Tryptophan biosynthesis |
| Lyase |
| Decarboxylase |
Gene Ontology
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| GO:0004425; Molecular function:indole-3-glycerol-phosphate synthase activity |
| GO:0000162; Biological process:tryptophan biosynthetic process |
Cross-references
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Features
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Additional information
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| Size range | 226-274 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: MF_00135 (trpF); MF_00211 (trpD) |
| Comments | Possible wrong start in THEKO, SYNY3 and VIBPA |