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HAMAP rule MF_00134

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General rule information [?]

Accession MF_00134
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 33)
Scope(s) Bacteria
Template(s) Q56319 (TRPC_THEMA); P00909 (TRPC_ECOLI); Q06121 (TRPC_SACS2); [ Recover all ]
Triggered by
case c? <OC:Bacteria>
HAMAP; MF_00134_B (Get profile general information and statistics)
end case
case c? <OC:Archaea>
HAMAP; MF_00134_A (Get profile general information and statistics)
end case

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier TRPC
Protein name RecName: Full=Indole-3-glycerol phosphate synthase;
Gene name Name=trpC;

Comments [?]

CATALYTIC ACTIVITY Reaction=1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O; Xref=Rhea:RHEA:23476, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:58613, ChEBI:CHEBI:58866; EC=;
PATHWAYAmino-acid biosynthesis; L-tryptophan biosynthesis; L- tryptophan from chorismate: step 4/5.
SIMILARITYBelongs to the TrpC family.

Keywords [?]

Gene Ontology [?]

GO:0004425; Molecular function:indole-3-glycerol-phosphate synthase activity
GO:0000162; Biological process:tryptophan biosynthetic process

Cross-references [?]

Pfam PF00218; IGPS; 1;

Features [?]

Additional information [?]

Size range 226-274 amino acids
Related rules None
Fusion Nter: None Cter: MF_00135 (trpF); MF_00211 (trpD)
Comments Possible wrong start in THEKO, SYNY3 and VIBPA

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