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| Annotation rule MF_00134 |
General rule information
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| Accession | MF_00134 |
| Dates | 1-JUN-2001 (Created) 18-NOV-2019 (Last updated, Version 33) |
| Name | IGPS |
| Scope | Bacteria
Archaea |
| Templates | Q56319 (TRPC_THEMA); P00909 (TRPC_ECOLI); Q06121 (TRPC_SACS2): [Recover all] |
case <OC:Bacteria>
| Triggered by |
end case
case <OC:Archaea>
| Triggered by |
end case
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Catalytic activity | RHEA:23476: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O
EC 4.1.1.48 |
| Pathway | Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. |
| Similarity | Belongs to the TrpC family. |
Keywords
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Amino-acid biosynthesis
Aromatic amino acid biosynthesis
Tryptophan biosynthesis
Lyase
Decarboxylase
Aromatic amino acid biosynthesis
Tryptophan biosynthesis
Lyase
Decarboxylase
Gene Ontology
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GO:0004425; Molecular function: indole-3-glycerol-phosphate synthase activity.
GO:0000162; Biological process: tryptophan biosynthetic process.
GO:0000162; Biological process: tryptophan biosynthetic process.
Cross-references
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Additional information
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case <OC:Bacteria>
| Size range | 250-305 amino acids |
end case
case <OC:Archaea>
| Size range | 226-274 amino acids |
end case
| Related rules | None |
| Fusion | Nter: None; Cter: MF_00135 (trpF), MF_00211 (trpD) |
| Comments | Possible wrong start in THEKO, SYNY3 and VIBPA |