HAMAP rule MF_00150
General rule information
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Accession | MF_00150 |
Dates | 1-JUN-2001 (Created) 18-NOV-2019 (Last updated, Version 43) |
Name | ArgC_type1 |
Scope | Bacteria
Archaea |
Template | P11446 (ARGC_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. |
Catalytic activity | RHEA:21588: N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH
EC 1.2.1.38 |
Pathway | Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. |
Keywords
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Gene Ontology
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GO:0003942; Molecular function: N-acetyl-gamma-glutamyl-phosphate reductase activity.
GO:0006526; Biological process: arginine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
GO:0006526; Biological process: arginine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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Features
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From: ARGC_ECOLI (P11446) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 154 | 154 | C |
Additional information
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Size range | 308-364 amino acids |
Related rules | MF_02083 (LYSY supersedes the current rule) |
Fusion | None |
Comments | See MF_01110 for ArgC type 2 subfamily. MF_00150 also matches LysY, which is a subfamily of ArgC type 1. MF_02083 is a child of MF_00150 and is specific for LysY. |