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Annotation rule MF_00164 |
General rule information
[?]
Accession |
MF_00164 |
Dates |
1-JUN-2001 (Created) 18-NOV-2019 (Last updated, Version 41) |
Scope |
Bacteria
Archaea
Plastid |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Protein name |
RecName:
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Full=Glutamine--fructose-6-phosphate aminotransferase [isomerizing];
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EC 2.6.1.16;
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AltName:
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Full=D-fructose-6-phosphate amidotransferase;
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AltName:
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Full=GFAT;
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AltName:
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Full=Glucosamine-6-phosphate synthase;
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AltName:
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Full=Hexosephosphate aminotransferase;
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AltName:
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Full=L-glutamine--D-fructose-6-phosphate amidotransferase;
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Function |
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. |
Catalytic activity |
RHEA:13237: D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate
EC 2.6.1.16
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Subunit |
Homodimer. |
case <OG:Chloroplast>
Subcellular location |
Plastid, chloroplast. |
end case
case not <OG:Chloroplast>
Subcellular location |
Cytoplasm. |
end case
case not <OG:Chloroplast>
end case
GO:0004360; Molecular function: glutamine-fructose-6-phosphate transaminase (isomerizing) activity.
GO:0005975; Biological process: carbohydrate metabolic process.
case <OG:Chloroplast>
end case
case not <OG:Chloroplast>
end case
From: GLMS_ECOLI (P17169) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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INIT_MET
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1
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1
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Removed
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M
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ACT_SITE
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2
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2
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Nucleophile; for GATase activity
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C
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ACT_SITE
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604
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604
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For Fru-6P isomerization activity
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K
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Additional information
[?]
Size range |
589-635 amino acids |
Related rules |
None |
Fusion |
None |
Comments |
Nodulating bacteria seem to have two copies: a glmS and a nodM. There does not seem to be any mean of distinguishing the two forms. Intein deleted in METJA (not shown in alignment). |