HAMAP rule MF_00170
General rule information
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| Accession | MF_00170 |
| Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 25) |
| Name | Rib_5P_isom_A |
| Scope(s) |
Bacteria Archaea |
| Template(s) | P0A7Z0 (RPIA_ECOLI); O50083 (RPIA_PYRHO); Q72J47 (RPIA_THET2); Q58998 (RPIA_METJA); [ Recover all ] |
| Triggered by |
HAMAP; MF_00170 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | RPIA |
| Protein name | RecName: Full=Ribose-5-phosphate isomerase A; EC=5.3.1.6; AltName: Full=Phosphoriboisomerase A; Short=PRI; |
| Gene name | Name=rpiA; |
Comments
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| FUNCTION | Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. |
| CATALYTIC ACTIVITY | Reaction=aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate; Xref=Rhea:RHEA:14657, ChEBI:CHEBI:58121, ChEBI:CHEBI:58273; EC=5.3.1.6; |
| PATHWAY | Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. |
| SUBUNIT | Homodimer. |
| SIMILARITY | Belongs to the ribose 5-phosphate isomerase family. |
Keywords
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Gene Ontology
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| GO:0004751; Molecular function:ribose-5-phosphate isomerase activity |
| GO:0009052; Biological process:pentose-phosphate shunt, non-oxidative branch |
Cross-references
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Features
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| From: RPIA_ECOLI (P0A7Z0) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 28 | 31 | /ligand="substrate" | x-G-x-T | ||||||||
| BINDING | 81 | 84 | /ligand="substrate" | D-x-x-D | ||||||||
| BINDING | 94 | 97 | /ligand="substrate" | K-G-x-G | ||||||||
| ACT_SITE | 103 | 103 | /note="Proton acceptor" | E | ||||||||
| BINDING | 121 | 121 | /ligand="substrate" | [KR] | ||||||||
Additional information
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| Size range | 215-262 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |