HAMAP logo

HAMAP rule MF_00170

Send feedback

General rule information [?]

Accession MF_00170
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 25)
Name Rib_5P_isom_A
Scope(s) Bacteria
Template(s) P0A7Z0 (RPIA_ECOLI); O50083 (RPIA_PYRHO); Q72J47 (RPIA_THET2); Q58998 (RPIA_METJA); [ Recover all ]
Triggered by HAMAP; MF_00170 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RPIA
Protein name RecName: Full=Ribose-5-phosphate isomerase A;
AltName: Full=Phosphoriboisomerase A;
Gene name Name=rpiA;

Comments [?]

FUNCTIONCatalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
CATALYTIC ACTIVITY Reaction=aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate; Xref=Rhea:RHEA:14657, ChEBI:CHEBI:58121, ChEBI:CHEBI:58273; EC=;
PATHWAYCarbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.
SIMILARITYBelongs to the ribose 5-phosphate isomerase family.

Keywords [?]

Gene Ontology [?]

GO:0004751; Molecular function:ribose-5-phosphate isomerase activity
GO:0009052; Biological process:pentose-phosphate shunt, non-oxidative branch

Cross-references [?]

Pfam PF00455; DeoRC; 0-1;
Pfam PF06026; Rib_5-P_isom_A; 1;
NCBIfam TIGR00021; RpiA; 1;

Features [?]

Key From To Description Tag Condition FTGroup
BINDING 28 31 /ligand="substrate" x-G-x-T
BINDING 81 84 /ligand="substrate" D-x-x-D
BINDING 94 97 /ligand="substrate" K-G-x-G
ACT_SITE 103 103 /note="Proton acceptor" E
BINDING 121 121 /ligand="substrate" [KR]

Additional information [?]

Size range 215-262 amino acids
Related rules None
Fusion Nter: None Cter: None

View rule in raw text format (no links)