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Annotation rule MF_00170
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General rule information [?]

Accession MF_00170
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 22)
Name Rib_5P_isom_A
Scope
Bacteria
Archaea
Templates P0A7Z0 (RPIA_ECOLI); O50083 (RPIA_PYRHO); Q72J47 (RPIA_THET2); Q58998 (RPIA_METJA): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
RPIA
Protein name
RecName: Full=Ribose-5-phosphate isomerase A;
EC 5.3.1.6;
AltName: Full=Phosphoriboisomerase A;
Short=PRI;
Gene name
rpiA

Comments [?]

Function Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
Catalytic activity RHEA:14657: aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate
EC 5.3.1.6
Pathway Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.
Subunit Homodimer.
Similarity Belongs to the ribose 5-phosphate isomerase family.

Keywords [?]


Gene Ontology [?]

GO:0004751; Molecular function: ribose-5-phosphate isomerase activity.
GO:0009052; Biological process: pentose-phosphate shunt, non-oxidative branch.

Cross-references [?]

Pfam PF00455; DeoRC; 0-1;
PF06026; Rib_5-P_isom_A; 1;
TIGRFAMs TIGR00021; RpiA; 1;

Features [?]

From: RPIA_ECOLI (P0A7Z0)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     28     31       Substrate binding     x-G-x-T  
REGION     81     84       Substrate binding     D-x-x-D  
REGION     94     97       Substrate binding     K-G-x-G  
ACT_SITE     103     103       Proton acceptor     E  
BINDING     121     121       Substrate     [KR]  

Additional information [?]

Size range 215-262 amino acids
Related rules None
Fusion None