HAMAP rule MF_00170

General rule information [?]

Accession	MF_00170
Dates	1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 25)

Name	Rib_5P_isom_A

Scope

Bacteria

Archaea

Templates

P0A7Z0 (RPIA_ECOLI); O50083 (RPIA_PYRHO); Q72J47 (RPIA_THET2); Q58998 (RPIA_METJA): [Recover all]

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

RPIA

Protein name

RecName:		Full=Ribose-5-phosphate isomerase A;
		EC 5.3.1.6;
AltName:		Full=Phosphoriboisomerase A;
		Short=PRI;

Gene name

rpiA

Comments [?]

Function	Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
Catalytic activity	RHEA:14657: aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate EC 5.3.1.6
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.
Subunit	Homodimer.
Similarity	Belongs to the ribose 5-phosphate isomerase family.

Keywords [?]

Gene Ontology [?]

GO:0004751; Molecular function: ribose-5-phosphate isomerase activity.
GO:0009052; Biological process: pentose-phosphate shunt, non-oxidative branch.

Cross-references [?]

Features [?]

From: RPIA_ECOLI (P0A7Z0)

Key From To Description Tag Condition FTGroup

BINDING 28 31 /ligand="substrate x-G-x-T

BINDING 81 84 /ligand="substrate D-x-x-D

BINDING 94 97 /ligand="substrate K-G-x-G

ACT_SITE 103 103 Proton acceptor E

BINDING 121 121 /ligand="substrate [KR]

Additional information [?]