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HAMAP rule MF_00175

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General rule information [?]

Accession MF_00175
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 28)
Name ClpX
Scope(s) Bacteria
Template(s) P0A6H1 (CLPX_ECOLI); O25926 (CLPX_HELPY); [ Recover all ]
Triggered by HAMAP; MF_00175 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier CLPX
Protein name RecName: Full=ATP-dependent Clp protease ATP-binding subunit ClpX;
Gene name Name=clpX;

Comments [?]

FUNCTIONATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
SUBUNITComponent of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
SIMILARITYBelongs to the ClpX chaperone family.

Keywords [?]

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0051082; Molecular function:unfolded protein binding
GO:0006457; Biological process:protein folding

Cross-references [?]

Pfam PF00004; AAA; 1;
Pfam PF06689; zf-C4_ClpX; 1;
NCBIfam TIGR00382; clpX; 1;

Features [?]

Key From To Description Tag Condition FTGroup
BINDING 120 127 /ligand="ATP"
BINDING 15 15 /ligand="Zn(2+)"
C 1
BINDING 18 18 /ligand="Zn(2+)"
C 1
BINDING 37 37 /ligand="Zn(2+)"
C 1
BINDING 40 40 /ligand="Zn(2+)"
C 1

Additional information [?]

Size range 380-500 amino acids
Related rules MF_00249
Fusion Nter: None Cter: None
Comments Unknown insert in BIFLO

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