HAMAP rule MF_00185
General rule information
[?]
Accession | MF_00185 |
Dates | 1-JUN-2001 (Created) 19-NOV-2022 (Last updated, Version 33) |
Name | IPP_trans |
Scope | Bacteria |
Template | P16384 (MIAA_ECOLI) |
Triggered by |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier |
|
Protein name |
|
Gene name |
|
Comments
[?]
Function | Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A). |
Catalytic activity | RHEA:26482: adenosine(37) in tRNA + dimethylallyl diphosphate = diphosphate + N(6)-dimethylallyladenosine(37) in tRNA
EC 2.5.1.75 |
Cofactor | Mg(2+) |
Subunit | Monomer. |
Similarity | Belongs to the IPP transferase family. |
Keywords
[?]
Gene Ontology
[?]
GO:0005524; Molecular function: ATP binding.
GO:0052381; Molecular function: tRNA dimethylallyltransferase activity.
GO:0008033; Biological process: tRNA processing.
GO:0052381; Molecular function: tRNA dimethylallyltransferase activity.
GO:0008033; Biological process: tRNA processing.
Cross-references
[?]
Features
[?]
From: MIAA_ECOLI (P16384) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 17 | 24 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 | |||||||||
BINDING (Optional) | 19 | 24 | /ligand="substrate | [ST]-x-x-[GN]-K-[ST] | ||||||||
REGION (Optional) | 42 | 45 | Interaction with substrate tRNA | D-S-x-x | ||||||||
REGION (Optional) | 166 | 170 | Interaction with substrate tRNA | Q-R-x-x-R | ||||||||
REGION (Optional) | 247 | 252 | Interaction with substrate tRNA | R-C-V-G-Y-R | ||||||||
REGION (Optional) | 280 | 287 | Interaction with substrate tRNA | K-R-Q-I-T-W-L-R | ||||||||
SITE (Optional) | 108 | 108 | Interaction with substrate tRNA | [TS] | ||||||||
SITE (Optional) | 130 | 130 | Interaction with substrate tRNA | R |
Additional information
[?]
Size range | 279-363 amino acids |
Related rules | None |
Fusion | None |
Comments | Possible wrong start in a number of cases |