 |
|
Annotation rule MF_00187 |
General rule information
[?]
Accession |
MF_00187 |
Dates |
1-JUN-2001 (Created) 18-NOV-2019 (Last updated, Version 23) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
case <FTTag:persulfide>
Protein name |
RecName:
|
Full=Sulfur carrier protein FdhD;
|
|
else
Protein name |
RecName:
|
Full=Protein FdhD;
|
|
end case
case <FTTag:persulfide>
Function |
Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. |
else
Function |
Required for formate dehydrogenase (FDH) activity. |
end case
Subcellular location |
Cytoplasm. |
Similarity |
Belongs to the FdhD family. |
case <FTTag:persulfide>
GO:0097163; Molecular function: sulfur carrier activity.
end case
GO:0006777; Biological process: Mo-molybdopterin cofactor biosynthetic process.
From: FDHD_ECOLI (P32177) |
Key
|
|
From
|
|
To
|
|
Description
|
|
Tag
|
|
Condition
|
|
FTGroup
|
REGION (Optional)
|
|
260
|
|
265
|
|
Mo-bisPGD binding
|
|
|
|
F-x-[KR]-x-x-[KR]
|
|
|
ACT_SITE
|
|
121
|
|
121
|
|
Cysteine persulfide intermediate
|
|
persulfide
|
|
C
|
|
|
Additional information
[?]
Size range |
220-340 amino acids |
Related rules |
None |
Fusion |
None |
Comments |
In some species, the catalytic cysteine loop is missing. In these species, FdhD may function as a chaperone involved in FDH maturation. See PubMed=25649206. |