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Annotation rule MF_00205 |
General rule information
[?]
Accession |
MF_00205 |
Dates |
1-JUN-2001 (Created) 18-NOV-2019 (Last updated, Version 35) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Protein name |
RecName:
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Full=UvrABC system protein A;
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Short=UvrA protein;
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AltName:
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Full=Excinuclease ABC subunit A;
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Function |
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. |
Subunit |
Forms a heterotetramer with UvrB during the search for lesions. |
Subcellular location |
Cytoplasm. |
Similarity |
Belongs to the ABC transporter superfamily. UvrA family. |
case <FTTag:zinc>
end case
case <FTTag:zinc>
end case
From: UVRA_ECOLI (P0A698) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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DOMAIN
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310
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587
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ABC transporter 1
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DOMAIN
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607
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937
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ABC transporter 2
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NP_BIND
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31
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38
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ATP
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G-x-S-G-S-G-K-S
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ZN_FING
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253
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280
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C4-type
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zinc
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C-x(2,3)-[CH]-x(20)-C-x(2)-C
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NP_BIND
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640
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647
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ATP
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|
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G-x-S-G-[GS]-G-K-S
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ZN_FING
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740
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766
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C4-type
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zinc
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C-x(2)-C-x(19)-C-x(2)-C
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Additional information
[?]
Size range |
900-1100 amino acids |
Related rules |
None |
Fusion |
None |
Comments |
Internal duplication in CHLPN and CHLTR. These sequences were not used in the alignment as both half of these sequences are divergent compared to other uvrA |