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Annotation rule MF_00209 |
General rule information
[?]
Accession |
MF_00209 |
Dates |
1-JUN-2001 (Created) 18-NOV-2019 (Last updated, Version 32) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Protein name |
RecName:
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Full=Inorganic pyrophosphatase;
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EC 3.6.1.1;
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AltName:
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Full=Pyrophosphate phospho-hydrolase;
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Short=PPase;
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|
Function |
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. |
Catalytic activity |
RHEA:24576: diphosphate + H2O = H(+) + 2 phosphate
EC 3.6.1.1
|
Cofactor |
Mg(2+) |
Subunit |
Homohexamer. |
Subcellular location |
Cytoplasm. |
Similarity |
Belongs to the PPase family. |
GO:0004427; Molecular function: inorganic diphosphatase activity.
GO:0000287; Molecular function: magnesium ion binding.
GO:0005737; Cellular component: cytoplasm.
case <OC:Actinobacteria>
From: IPYR_MYCTU (P9WI55) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
|
ACT_SITE
|
|
89
|
|
89
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|
Proton acceptor
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|
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|
D
|
|
|
METAL
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|
8
|
|
8
|
|
Magnesium 2
|
|
|
|
E
|
|
|
METAL
|
|
52
|
|
52
|
|
Magnesium 1
|
|
|
|
D
|
|
|
METAL
|
|
57
|
|
57
|
|
Magnesium 1
|
|
|
|
D
|
|
|
METAL
|
|
57
|
|
57
|
|
Magnesium 2
|
|
|
|
D
|
|
|
METAL
|
|
84
|
|
84
|
|
Magnesium 3
|
|
|
|
D
|
|
|
METAL
|
|
89
|
|
89
|
|
Magnesium 1
|
|
|
|
D
|
|
|
METAL
|
|
89
|
|
89
|
|
Magnesium 3
|
|
|
|
D
|
|
|
end case
BINDING
|
|
16
|
|
16
|
|
Substrate
|
|
|
|
K
|
|
|
BINDING
|
|
30
|
|
30
|
|
Substrate
|
|
|
|
R
|
|
|
BINDING
|
|
42
|
|
42
|
|
Substrate
|
|
|
|
Y
|
|
|
BINDING
|
|
126
|
|
126
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|
Substrate
|
|
|
|
Y
|
|
|
case not <OC:Actinobacteria>
From: IPYR_ECOLI (P0A7A9) |
METAL
|
|
66
|
|
66
|
|
Magnesium 1
|
|
|
|
D
|
|
|
METAL
|
|
71
|
|
71
|
|
Magnesium 1
|
|
|
|
D
|
|
|
METAL
|
|
71
|
|
71
|
|
Magnesium 2
|
|
|
|
D
|
|
|
METAL
|
|
103
|
|
103
|
|
Magnesium 1
|
|
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D
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end case
Additional information
[?]
Size range |
158-215 amino acids |
Related rules |
None |
Fusion |
None |