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| Annotation rule MF_00227 |
General rule information
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| Accession | MF_00227 |
| Dates | 1-JUN-2001 (Created) 18-NOV-2019 (Last updated, Version 21) |
| Name | RNase_P |
| Scope | Bacteria |
| Templates | P25814 (RNPA_BACSU); P0A0H5 (RNPA_STAAU): [Recover all] |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. |
| Catalytic activity | Reaction=Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.; EC=3.1.26.5; |
| Subunit | Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit. |
| Similarity | Belongs to the RnpA family. |
Keywords
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Gene Ontology
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GO:0004526; Molecular function: ribonuclease P activity.
GO:0000049; Molecular function: tRNA binding.
GO:0001682; Biological process: tRNA 5'-leader removal.
GO:0000049; Molecular function: tRNA binding.
GO:0001682; Biological process: tRNA 5'-leader removal.
Cross-references
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Additional information
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| Size range | 108-166 amino acids |
| Related rules | None |
| Fusion | None |