HAMAP rule MF_00253
General rule information
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Accession | MF_00253 |
Dates | 1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 31) |
Name | Gly_tRNA_synth |
Scope | Bacteria
Archaea |
Template | P56206 (SYG_THET8) |
case <OC:Bacteria>
Triggered by |
end case
case <OC:Archaea>
Triggered by |
end case
Propagated annotation
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Identifier, protein and gene names
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Identifier |
|
Protein name |
|
case <OC:Bacteria>
Gene name |
|
end case
case <OC:Archaea>
Gene name |
|
end case
Comments
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Function | Catalyzes the attachment of glycine to tRNA(Gly). |
Catalytic activity | RHEA:16013: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)
EC 6.1.1.14 |
case <OC:Bacteria>
Subunit | Homodimer. |
end case
Subcellular location | Cytoplasm. |
Similarity | Belongs to the class-II aminoacyl-tRNA synthetase family. |
Keywords
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Gene Ontology
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GO:0005524; Molecular function: ATP binding.
GO:0004820; Molecular function: glycine-tRNA ligase activity.
GO:0006426; Biological process: glycyl-tRNA aminoacylation.
GO:0005737; Cellular component: cytoplasm.
GO:0004820; Molecular function: glycine-tRNA ligase activity.
GO:0006426; Biological process: glycyl-tRNA aminoacylation.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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Pfam | PF00587; tRNA-synt_2b; 1; |
PRINTS | PR01043; TRNASYNTHGLY; 1; |
NCBIfam | TIGR00389; GlyS_dimeric; 1; |
PROSITE | PS50862; AA_TRNA_LIGASE_II; 1; |
Features
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case <OC:Bacteria>
From: SYG_THET8 (P56206) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 221 | 223 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 | R-N-E | ||||||||
BINDING | 231 | 236 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 | [FILV]-R-x(3)-[FL] | ||||||||
BINDING | 305 | 306 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 | E-[CILV] | ||||||||
BINDING | 364 | 367 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 | G-x(2)-R | ||||||||
BINDING | 236 | 240 | /ligand="substrate | [FL]-x-Q-x-E | ||||||||
BINDING | 360 | 364 | /ligand="substrate | E-x(3)-G | ||||||||
BINDING | 99 | 99 | /ligand="substrate | [KR] | ||||||||
BINDING | 189 | 189 | /ligand="substrate | E |
end case
case <OC:Archaea>
From: SYG_METJA (Q57681) | ||||||||||||
BINDING | 196 | 198 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 | R-N-E | ||||||||
BINDING | 206 | 211 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 | [FILV]-R-x(3)-F | ||||||||
BINDING | 328 | 329 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 | E-[CILV] | ||||||||
BINDING | 451 | 454 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 | G-x(2)-R | ||||||||
BINDING | 211 | 215 | /ligand="substrate | F-x(3)-E | ||||||||
BINDING | 447 | 451 | /ligand="substrate | E-x(3)-G | ||||||||
BINDING | 98 | 98 | /ligand="substrate | R | ||||||||
BINDING | 164 | 164 | /ligand="substrate | E |
end case
Additional information
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case <OC:Bacteria>
Size range | 445-506 amino acids |
end case
case <OC:Archaea>
Size range | 565-583 amino acids |
end case
Related rules | None |
Fusion | None |