HAMAP rule MF_00254

General rule information [?]

Accession	MF_00254
Dates	1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 26)

Name	Gly_tRNA_synth_alpha

Scope

Bacteria

Template

O23627 (SYGM1_ARATH)

Triggered by

HAMAP; MF_00254 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

SYGA

Protein name

RecName:		Full=Glycine--tRNA ligase alpha subunit;
		EC 6.1.1.14;
AltName:		Full=Glycyl-tRNA synthetase alpha subunit;
		Short=GlyRS;

Gene name

glyQ

Comments [?]

Catalytic activity	RHEA:16013: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly) EC 6.1.1.14
Subunit	Tetramer of two alpha and two beta subunits.
Subcellular location	Cytoplasm.
Similarity	Belongs to the class-II aminoacyl-tRNA synthetase family.

Keywords [?]

Cytoplasm
Aminoacyl-tRNA synthetase
Protein biosynthesis
Ligase
ATP-binding
Nucleotide-binding

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0004820; Molecular function: glycine-tRNA ligase activity.
GO:0006426; Biological process: glycyl-tRNA aminoacylation.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam	PF02091; tRNA-synt_2e; 1;
PRINTS	PR01044; TRNASYNTHGA; 1;
NCBIfam	TIGR00388; GlyQ; 1;
PROSITE	PS50861; AA_TRNA_LIGASE_II_GLYAB; 1;

Additional information [?]

Size range	285-319 amino acids
Related rules	None
Fusion	Nter: None; Cter: MF_00255 (glyS)
Comments	glyQ and glyS are fused in Chlamydia. Possible wrong start in XYLFA.

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