HAMAP rule MF_00270
General rule information
[?]
| PURL | https://purl.expasy.org/hamap/rule/MF_00270 |
| Accession | MF_00270 |
| Dates | 28-FEB-2005 (Created)
03-NOV-2025 (Last updated, Version ) |
| Name | Ribosomal_bS18 |
| Scope(s) |
Bacteria Plastid |
| Template(s) | P0A7T7; Q5SLQ0; P9WH49; [ Recover all ] |
| Triggered by |
case c? <OC:Bacteria> or <OG:Chloroplast>
HAMAP; MF_00270 (Get profile general information and statistics) end case
|
Propagated annotation
[?]
Identifier, protein and gene names
[?]
| case <OC:Bacteria> and not <OC:Cyanobacteriota> | |
| Identifier | RS18 |
| Protein name | RecName: Full=Small ribosomal subunit protein bS18; |
| Gene name | Name=rpsR; |
| else case <OC:Cyanobacteriota> | |
| Identifier | RS18 |
| Protein name | RecName: Full=Small ribosomal subunit protein bS18; |
| Gene name | Name=rpsR; Synonyms=rps18; |
| else case <OG:Chloroplast> | |
| Identifier | RR18 |
| Protein name | RecName: Full=Small ribosomal subunit protein bS18c; |
| Gene name | Name=rps18; |
| end case | |
Comments
[?]
| case <OC:Bacteria> | |
| FUNCTION | Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit. |
| SUBUNIT | Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. |
| end case | |
| case <FTGroup:1> | |
| COFACTOR | Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 1 Zn(2+) ion per subunit.; |
| end case | |
| case <OG:Chloroplast> | |
| SUBUNIT | Part of the 30S ribosomal subunit. |
| SUBCELLULAR LOCATION | Plastid, chloroplast. |
| end case | |
| SIMILARITY | Belongs to the bacterial ribosomal protein bS18 family. |
Keywords
[?]
| Ribonucleoprotein | |
| Ribosomal protein | |
| RNA-binding | |
| rRNA-binding | |
| case <FTGroup:1> | |
| Zinc | |
| Metal-binding | |
| end case | |
Gene Ontology
[?]
| GO:0019843; Molecular function:rRNA binding | |
| GO:0006412; Biological process:translation | |
| case <OG:Chloroplast> | |
| GO:0009507; Cellular component:chloroplast | |
| end case | |
| case <FTGroup:1> | |
| GO:0008270; Molecular function:zinc ion binding | |
| end case | |
Cross-references
[?]
| Pfam | PF01084; Ribosomal_S18; 1; |
| PRINTS | PR00974; RIBOSOMALS18; 1; |
| NCBIfam | TIGR00165; S18; 1; |
| PROSITE | PS00057; RIBOSOMAL_S18; 1; |
Features
[?]
| From: RS181_MYCTU (P9WH49) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 20 | 20 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
| BINDING | 23 | 23 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
| BINDING | 57 | 57 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
| BINDING | 60 | 60 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
[CH] | 1 | |||||||
Additional information
[?]
| Size range | 68-171 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | As suggested in Ban et al., (2014, PMID 24524803), capital letters directly following protein names are used to distinguish different isoforms of the same protein. |