HAMAP rule MF_00316
General rule information
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Accession | MF_00316 |
Dates | 1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 35) |
Name | MobA |
Scope | Bacteria
Archaea |
Template | P32173 (MOBA_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
|
case <OC:Pseudomonadota>
Protein name |
|
else
Protein name |
|
end case
Gene name |
|
Comments
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Function | Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. |
Catalytic activity | RHEA:34243: GTP + H(+) + Mo-molybdopterin = diphosphate + Mo-molybdopterin guanine dinucleotide
EC 2.7.7.77 |
Cofactor | Mg(2+) |
case <OC:Pseudomonadota>
Subunit | Monomer. |
end case
Domain | The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the MobA family. |
Keywords
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Cytoplasm
GTP-binding
Magnesium
Metal-binding
Molybdenum cofactor biosynthesis
Nucleotide-binding
Transferase
GTP-binding
Magnesium
Metal-binding
Molybdenum cofactor biosynthesis
Nucleotide-binding
Transferase
Gene Ontology
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GO:0005525; Molecular function: GTP binding.
GO:0070568; Molecular function: guanylyltransferase activity.
GO:0019720; Biological process: Mo-molybdopterin cofactor metabolic process.
GO:0005737; Cellular component: cytoplasm.
GO:0070568; Molecular function: guanylyltransferase activity.
GO:0019720; Biological process: Mo-molybdopterin cofactor metabolic process.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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NCBIfam | TIGR02665; Molyb_mobA; 1; |
Features
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From: MOBA_ECOLI (P32173) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 12 | 14 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565 | [LFIVT]-x-G | ||||||||
BINDING | 101 | 101 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420 | D | ||||||||
BINDING | 25 | 25 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565 | [KR] | ||||||||
BINDING (Optional) | 53 | 53 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565 | [NRHK] | ||||||||
BINDING (Optional) | 71 | 71 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565 | D | ||||||||
BINDING | 101 | 101 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565 | D |
Additional information
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Size range | 189-225 amino acids |
Related rules | None |
Fusion | Nter: MF_01224 (moaC); Cter: None |