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Annotation rule MF_00316
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General rule information [?]

Accession MF_00316
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 31)
Name MobA
Scope
Bacteria
Archaea
Template P32173 (MOBA_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
MOBA
case <OC:Proteobacteria>
Protein name
RecName: Full=Molybdenum cofactor guanylyltransferase;
Short=MoCo guanylyltransferase;
EC 2.7.7.77;
AltName: Full=GTP:molybdopterin guanylyltransferase;
AltName: Full=Molybdopterin-guanine dinucleotide synthase;
Short=MGD synthase;
AltName: Full=Molybdopterin guanylyltransferase;
AltName: Full=Mo-MPT guanylyltransferase;
else
Protein name
RecName: Full=Probable molybdenum cofactor guanylyltransferase;
Short=MoCo guanylyltransferase;
EC 2.7.7.77;
AltName: Full=GTP:molybdopterin guanylyltransferase;
AltName: Full=Molybdopterin-guanine dinucleotide synthase;
Short=MGD synthase;
AltName: Full=Molybdopterin guanylyltransferase;
AltName: Full=Mo-MPT guanylyltransferase;
end case
Gene name
mobA

Comments [?]

Function Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
Catalytic activity RHEA:34243: GTP + H(+) + Mo-molybdopterin = diphosphate + Mo-molybdopterin guanine dinucleotide
EC 2.7.7.77
Cofactor Mg(2+)
case <OC:Proteobacteria>
Subunit Monomer.
end case
Domain The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
Subcellular location Cytoplasm.
Similarity Belongs to the MobA family.

Keywords [?]

Cytoplasm
GTP-binding
Magnesium
Metal-binding
Molybdenum cofactor biosynthesis
Nucleotide-binding
Transferase

Gene Ontology [?]

GO:0005525; Molecular function: GTP binding.
GO:0070568; Molecular function: guanylyltransferase activity.
GO:0019720; Biological process: Mo-molybdopterin cofactor metabolic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

TIGRFAMs TIGR02665; Molyb_mobA; 1;

Features [?]

From: MOBA_ECOLI (P32173)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     12     14       GTP     [LFIVT]-x-G  
METAL     101     101       Magnesium     D  
BINDING     25     25       GTP     [KR]  
BINDING (Optional)     53     53       GTP     [NRHK]  
BINDING (Optional)     71     71       GTP     D  
BINDING     101     101       GTP     D  

Additional information [?]

Size range 189-225 amino acids
Related rules None
Fusion Nter: MF_01224 (moaC); Cter: None


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