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Annotation rule MF_00320
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General rule information [?]

Accession MF_00320
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 26)
Name RNApol_arch_D
Scope
Archaea
Templates Q9HQJ4 (RPOD_HALSA); P95989 (RPOD_SACS2): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
RPOD
Protein name
RecName: Full=DNA-directed RNA polymerase subunit D;
EC 2.7.7.6;
Gene name
rpoD

Comments [?]

Function DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Catalytic activity RHEA:21248: a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)
EC 2.7.7.6
case <FTGroup:1>
Cofactor [4Fe-4S] cluster
Note: Binds 1 [4Fe-4S] cluster.
end case
Similarity Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.

Keywords [?]

DNA-directed RNA polymerase
case <FTGroup:1>
4Fe-4S
Iron
Iron-sulfur
Metal-binding
end case
Nucleotidyltransferase
Transcription
Transferase

Gene Ontology [?]

GO:0003677; Molecular function: DNA binding.
GO:0003899; Molecular function: DNA-directed 5'-3' RNA polymerase activity.
case <FTGroup:1>
GO:0051536; Molecular function: iron-sulfur cluster binding.
end case
GO:0006351; Biological process: transcription, DNA-templated.

Cross-references [?]

PROSITE PS00446; RNA_POL_D_30KD; 1;
PS00198; 4FE4S_FER_1; 0-1;
PS51379; 4FE4S_FER_2; 0-1;
Pfam PF01000; RNA_pol_A_bac; 1;
PF01193; RNA_pol_L; 1;

Features [?]

From: RPOD_SACS2 (P95989)
Key     From     To       Description   Tag   Condition   FTGroup
METAL (Optional)     183     183       Iron-sulfur (4Fe-4S)     C   1
METAL (Optional)     203     203       Iron-sulfur (4Fe-4S)     C   1
METAL (Optional)     206     206       Iron-sulfur (4Fe-4S)     C   1
METAL (Optional)     209     209       Iron-sulfur (4Fe-4S)     C   1

Additional information [?]

Size range 191-290 amino acids
Related rules None
Fusion None


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