HAMAP rule MF_00320

General rule information [?]

Accession	MF_00320
Dates	1-JUN-2001 (Created) 19-NOV-2022 (Last updated, Version 31)

Name	RNApol_arch_Rpo3

Scope

Archaea

Templates

P95989 (RPO3_SACS2); B8YB56 (RPO3_SACSH); P39471 (RPO3_SULAC); Q5JJF4 (RPO3_THEKO): [Recover all]

Triggered by

HAMAP; MF_00320 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

RPO3

Protein name

RecName:		Full=DNA-directed RNA polymerase subunit Rpo3;
		EC 2.7.7.6;
AltName:		Full=DNA-directed RNA polymerase subunit D;

Gene name

rpo3, rpoD

Comments [?]

Function	DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Catalytic activity	RHEA:21248: a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1) EC 2.7.7.6

case <FTGroup:1>

Cofactor

[3Fe-4S] cluster
Note: Binds 1 [3Fe-4S] cluster.

end case

Subunit	Part of the RNA polymerase complex.
Subcellular location	Cytoplasm.
Similarity	Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

Keywords [?]

Cytoplasm
DNA-directed RNA polymerase

case <FTGroup:1>

3Fe-4S
Iron
Iron-sulfur
Metal-binding

end case

Nucleotidyltransferase
Transcription
Transferase

Gene Ontology [?]

GO:0005737; Cellular component: cytoplasm.
GO:0003677; Molecular function: DNA binding.
GO:0003899; Molecular function: DNA-directed 5'-3' RNA polymerase activity.

case <FTGroup:1>

GO:0051536; Molecular function: iron-sulfur cluster binding.

end case

GO:0006351; Biological process: DNA-templated transcription.

Cross-references [?]

PROSITE	PS00446; RNA_POL_D_30KD; 1;
	PS00198; 4FE4S_FER_1; 0-1;
	PS51379; 4FE4S_FER_2; 0-1;
Pfam	PF01000; RNA_pol_A_bac; 1;
	PF01193; RNA_pol_L; 1;

Features [?]

From: RPO3_SACS2 (P95989)

Key From To Description Tag Condition FTGroup

BINDING (Optional) 203 203 /ligand="[3Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:21137 C 1

BINDING (Optional) 206 206 /ligand="[3Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:21137 C 1

BINDING (Optional) 209 209 /ligand="[3Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:21137 C 1

Additional information [?]

Size range	191-305 amino acids
Related rules	None
Fusion	None

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