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HAMAP rule MF_00320

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General rule information [?]

Accession MF_00320
Dates 1-JUN-2001 (Created)
19-NOV-2022 (Last updated, Version 31)
Name RNApol_arch_Rpo3
Templates P95989 (RPO3_SACS2); B8YB56 (RPO3_SACSH); P39471 (RPO3_SULAC); Q5JJF4 (RPO3_THEKO): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=DNA-directed RNA polymerase subunit Rpo3;
AltName: Full=DNA-directed RNA polymerase subunit D;
Gene name
rpo3, rpoD

Comments [?]

Function DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Catalytic activity RHEA:21248: a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)
case <FTGroup:1>
Cofactor [3Fe-4S] cluster
Note: Binds 1 [3Fe-4S] cluster.
end case
Subunit Part of the RNA polymerase complex.
Subcellular location Cytoplasm.
Similarity Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

Keywords [?]

case <FTGroup:1>
end case

Gene Ontology [?]

GO:0005737; Cellular component: cytoplasm.
GO:0003677; Molecular function: DNA binding.
GO:0003899; Molecular function: DNA-directed 5'-3' RNA polymerase activity.
case <FTGroup:1>
GO:0051536; Molecular function: iron-sulfur cluster binding.
end case
GO:0006351; Biological process: DNA-templated transcription.

Cross-references [?]

PS00198; 4FE4S_FER_1; 0-1;
PS51379; 4FE4S_FER_2; 0-1;
Pfam PF01000; RNA_pol_A_bac; 1;
PF01193; RNA_pol_L; 1;

Features [?]

From: RPO3_SACS2 (P95989)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING (Optional)     203     203       /ligand="[3Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:21137     C   1
BINDING (Optional)     206     206       /ligand="[3Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:21137     C   1
BINDING (Optional)     209     209       /ligand="[3Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:21137     C   1

Additional information [?]

Size range 191-305 amino acids
Related rules None
Fusion None