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HAMAP rule MF_00320

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General rule information [?]

Accession MF_00320
Dates 1-JUN-2001 (Created)
19-NOV-2022 (Last updated, Version 31)
Name RNApol_arch_Rpo3
Scope(s) Archaea
Template(s) P95989 (RPO3_SACS2); B8YB56 (RPO3_SACSH); P39471 (RPO3_SULAC); Q5JJF4 (RPO3_THEKO); [ Recover all ]
Triggered by HAMAP; MF_00320 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RPO3
Protein name RecName: Full=DNA-directed RNA polymerase subunit Rpo3;
AltName: Full=DNA-directed RNA polymerase subunit D;
Gene name Name=rpo3; Synonyms=rpoD;

Comments [?]

FUNCTIONDNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
CATALYTIC ACTIVITY Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA- COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395; EC=;
case <FTGroup:1>
COFACTOR Name=[3Fe-4S] cluster; Xref=ChEBI:CHEBI:21137; Note=Binds 1 [3Fe-4S] cluster.;
end case
SUBUNITPart of the RNA polymerase complex.
SIMILARITYBelongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

Keywords [?]

Gene Ontology [?]

GO:0005737; Cellular component:cytoplasm
GO:0003677; Molecular function:DNA binding
GO:0003899; Molecular function:DNA-directed 5'-3' RNA polymerase activity
case <FTGroup:1>
GO:0051536; Molecular function:iron-sulfur cluster binding
end case
GO:0006351; Biological process:DNA-templated transcription

Cross-references [?]

PROSITE PS00198; 4FE4S_FER_1; 0-1;
PROSITE PS51379; 4FE4S_FER_2; 0-1;
Pfam PF01000; RNA_pol_A_bac; 1;
Pfam PF01193; RNA_pol_L; 1;

Features [?]

From: RPO3_SACS2 (P95989)
Key From To Description Tag Condition FTGroup
BINDING 203 203 /ligand="[3Fe-4S] cluster"
C 1
BINDING 206 206 /ligand="[3Fe-4S] cluster"
C 1
BINDING 209 209 /ligand="[3Fe-4S] cluster"
C 1

Additional information [?]

Size range 191-305 amino acids
Related rules None
Fusion Nter: None Cter: None

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