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Annotation rule MF_00328
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General rule information [?]

Accession MF_00328
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 25)
Name Guanylate_kinase
Scope
Bacteria
Templates P60546 (KGUA_ECOLI); P15454 (KGUA_YEAST): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
KGUA
Protein name
RecName: Full=Guanylate kinase;
EC 2.7.4.8;
AltName: Full=GMP kinase;
Gene name
gmk

Comments [?]

Function Essential for recycling GMP and indirectly, cGMP.
Catalytic activity RHEA:20780: ATP + GMP = ADP + GDP
EC 2.7.4.8
Subcellular location Cytoplasm.
Similarity Belongs to the guanylate kinase family.

Keywords [?]

Cytoplasm
Transferase
Kinase
ATP-binding
Nucleotide-binding

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0004385; Molecular function: guanylate kinase activity.
GO:0006163; Biological process: purine nucleotide metabolic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF00625; Guanylate_kin; 1;
TIGRFAMs TIGR03263; guanyl_kin; 1;
PROSITE PS00856; GUANYLATE_KINASE_1; 1;
PS50052; GUANYLATE_KINASE_2; 1; trigger=PRU00100;

Features [?]

From: KGUA_ECOLI (P60546)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     11     18       ATP     [GSA]-x-[SAT]-[GA]-x-G-K-x  

Additional information [?]

Size range 176-254 amino acids
Related rules None
Fusion Nter: None; Cter: <Unknown>
Comments Possible wrong start in MYCGE and MYCPN


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