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Annotation rule MF_00332
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General rule information [?]

Accession MF_00332
Dates 1-JUN-2001 (Created)
24-JUN-2016 (Last updated, Version 50)
Name DnaK
Scope
Bacteria
Archaea
Plastid
Template P0A6Y8 (DNAK_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
DNAK
Protein name
RecName: Full=Chaperone protein DnaK;
AltName: Full=HSP70;
AltName: Full=Heat shock 70 kDa protein;
AltName: Full=Heat shock protein 70;
Gene name
dnaK

Comments [?]

Function Acts as a chaperone.
case <OC:Bacteria>
Induction By stress conditions e.g. heat shock.
end case
case <OG:Chloroplast>
Subcellular location Plastid, chloroplast.
end case
Similarity Belongs to the heat shock protein 70 family.

Keywords [?]

case <FT:2> or <FT:3> or <FT:4> or <FT:5> or <FT:6>
Acetylation
end case
ATP-binding
Chaperone
Nucleotide-binding
case <OC:Bacteria>
Stress response
end case
case <OC:Bacteria> and <FT:1>
Phosphoprotein
end case

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case

Cross-references [?]

Pfam PF00012; HSP70; 1;
PRINTS PR00301; HEATSHOCK70; 1;
PROSITE PS00297; HSP70_1; 1;
PS00329; HSP70_2; 1;
PS01036; HSP70_3; 1;
TIGRFAMs TIGR02350; prok_dnaK; 1;

Features [?]

case <OC:Bacteria>
From: DNAK_ECOLI (P0A6Y8)
Key     From     To       Description   Tag   Condition   FTGroup
MOD_RES     199     199       Phosphothreonine; by autocatalysis     T  
end case
case <OC:Escherichia> or <OC:Shigella>
MOD_RES     109     109       N6-acetyllysine     K  
MOD_RES     245     245       N6-acetyllysine     K  
MOD_RES     304     304       N6-acetyllysine     K  
MOD_RES     421     421       N6-acetyllysine     K  
MOD_RES     556     556       N6-acetyllysine     K  
end case

Additional information [?]

Size range 591-771 amino acids
Related rules MF_00679 (HSCA)
Fusion None
Comments Cyanobacteria have 3 copies of dnaK, only the second one (dnaK2) is represented in this alignment. The two others are divergent and longer


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