HAMAP rule MF_00356

General rule information [?]

Accession	MF_00356
Dates	1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 32)

Name	DNApol_PolC

Scope

Bacteria

Templates

P13267 (DPO3_BACSU); P47729 (DPO3_MYCPU); P0C1P9 (DPO3_STAAU); Q2G1Z8 (DPO3_STAA8): [Recover all]

Triggered by

HAMAP; MF_00356 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

DPO3

Protein name

RecName:		Full=DNA polymerase III PolC-type;
		Short=PolIII;
		EC 2.7.7.7;

Gene name

polC

Comments [?]

Function	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
Catalytic activity	RHEA:22508: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1) EC 2.7.7.7
Subcellular location	Cytoplasm.
Similarity	Belongs to the DNA polymerase type-C family. PolC subfamily.

Keywords [?]

Cytoplasm
Transferase
Nucleotidyltransferase
DNA-directed DNA polymerase
DNA replication
Hydrolase
Nuclease
Exonuclease

Gene Ontology [?]

GO:0008408; Molecular function: 3'-5' exonuclease activity.
GO:0003677; Molecular function: DNA binding.
GO:0003887; Molecular function: DNA-directed DNA polymerase activity.
GO:0006261; Biological process: DNA-templated DNA replication.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam	PF07733; DNA_pol3_alpha; 1;
	PF00929; RNase_T; 1;
	PF02811; PHP; 1;
	PF01336; tRNA_anti; 1;
NCBIfam	TIGR00573; Dnaq; 1;
	TIGR01405; PolC_Gram_pos; 1;

Additional information [?]

Size range	1367-1638 amino acids
Related rules	None
Fusion	None
Comments	LACLA has a weird insertion not found in other polC.

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