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HAMAP rule MF_00356

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General rule information [?]

Accession MF_00356
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 32)
Name DNApol_PolC
Templates P13267 (DPO3_BACSU); P47729 (DPO3_MYCPU); P0C1P9 (DPO3_STAAU); Q2G1Z8 (DPO3_STAA8): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=DNA polymerase III PolC-type;
Gene name

Comments [?]

Function Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
Catalytic activity RHEA:22508: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)
Subcellular location Cytoplasm.
Similarity Belongs to the DNA polymerase type-C family. PolC subfamily.

Keywords [?]

Gene Ontology [?]

GO:0008408; Molecular function: 3'-5' exonuclease activity.
GO:0003677; Molecular function: DNA binding.
GO:0003887; Molecular function: DNA-directed DNA polymerase activity.
GO:0006261; Biological process: DNA-templated DNA replication.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF07733; DNA_pol3_alpha; 1;
PF00929; RNase_T; 1;
PF02811; PHP; 1;
PF01336; tRNA_anti; 1;
NCBIfam TIGR00573; Dnaq; 1;
TIGR01405; PolC_Gram_pos; 1;

Additional information [?]

Size range 1367-1638 amino acids
Related rules None
Fusion None
Comments LACLA has a weird insertion not found in other polC.