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| Annotation rule MF_00356 |
General rule information
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| Accession | MF_00356 |
| Dates | 1-JUN-2001 (Created) 18-NOV-2019 (Last updated, Version 29) |
| Name | DNApol_PolC |
| Scope | Bacteria |
| Templates | P13267 (DPO3_BACSU); P47729 (DPO3_MYCPU); P0C1P9 (DPO3_STAAU); Q2G1Z8 (DPO3_STAA8): [Recover all] |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. |
| Catalytic activity | RHEA:22508: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)
EC 2.7.7.7 |
| Subcellular location | Cytoplasm. |
| Similarity | Belongs to the DNA polymerase type-C family. PolC subfamily. |
Keywords
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Cytoplasm
Transferase
Nucleotidyltransferase
DNA-directed DNA polymerase
DNA replication
Hydrolase
Nuclease
Exonuclease
Transferase
Nucleotidyltransferase
DNA-directed DNA polymerase
DNA replication
Hydrolase
Nuclease
Exonuclease
Gene Ontology
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GO:0008408; Molecular function: 3'-5' exonuclease activity.
GO:0003677; Molecular function: DNA binding.
GO:0003887; Molecular function: DNA-directed DNA polymerase activity.
GO:0006261; Biological process: DNA-dependent DNA replication.
GO:0005737; Cellular component: cytoplasm.
GO:0003677; Molecular function: DNA binding.
GO:0003887; Molecular function: DNA-directed DNA polymerase activity.
GO:0006261; Biological process: DNA-dependent DNA replication.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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| Pfam | PF07733; DNA_pol3_alpha; 1; |
| PF00929; RNase_T; 1; | |
| PF02811; PHP; 1; | |
| PF01336; tRNA_anti; 1; | |
| TIGRFAMs | TIGR00573; Dnaq; 1; |
| TIGR01405; PolC_Gram_pos; 1; |
Additional information
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| Size range | 1367-1638 amino acids |
| Related rules | None |
| Fusion | None |
| Comments | LACLA has a weird insertion not found in other polC. |