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HAMAP rule MF_00356

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General rule information [?]

Accession MF_00356
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 32)
Name DNApol_PolC
Scope(s) Bacteria
Template(s) P13267 (DPO3_BACSU); P47729 (DPO3_MYCPU); P0C1P9 (DPO3_STAAU); Q2G1Z8 (DPO3_STAA8); [ Recover all ]
Triggered by HAMAP; MF_00356 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier DPO3
Protein name RecName: Full=DNA polymerase III PolC-type;
Gene name Name=polC;

Comments [?]

FUNCTIONRequired for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
CATALYTIC ACTIVITY Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339, Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560, ChEBI:CHEBI:173112; EC=;
SIMILARITYBelongs to the DNA polymerase type-C family. PolC subfamily.

Keywords [?]

Gene Ontology [?]

GO:0008408; Molecular function:3'-5' exonuclease activity
GO:0003677; Molecular function:DNA binding
GO:0003887; Molecular function:DNA-directed DNA polymerase activity
GO:0006261; Biological process:DNA-templated DNA replication
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF07733; DNA_pol3_alpha; 1;
Pfam PF00929; RNase_T; 1;
Pfam PF02811; PHP; 1;
Pfam PF01336; tRNA_anti; 1;
NCBIfam TIGR00573; Dnaq; 1;
NCBIfam TIGR01405; PolC_Gram_pos; 1;

Features [?]

Additional information [?]

Size range 1367-1638 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments LACLA has a weird insertion not found in other polC.

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