HAMAP rule MF_00356
General rule information
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Accession | MF_00356 |
Dates | 1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 32) |
Name | DNApol_PolC |
Scope | Bacteria |
Templates | P13267 (DPO3_BACSU); P47729 (DPO3_MYCPU); P0C1P9 (DPO3_STAAU); Q2G1Z8 (DPO3_STAA8): [Recover all] |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. |
Catalytic activity | RHEA:22508: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)
EC 2.7.7.7 |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the DNA polymerase type-C family. PolC subfamily. |
Keywords
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Cytoplasm
Transferase
Nucleotidyltransferase
DNA-directed DNA polymerase
DNA replication
Hydrolase
Nuclease
Exonuclease
Transferase
Nucleotidyltransferase
DNA-directed DNA polymerase
DNA replication
Hydrolase
Nuclease
Exonuclease
Gene Ontology
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GO:0008408; Molecular function: 3'-5' exonuclease activity.
GO:0003677; Molecular function: DNA binding.
GO:0003887; Molecular function: DNA-directed DNA polymerase activity.
GO:0006261; Biological process: DNA-templated DNA replication.
GO:0005737; Cellular component: cytoplasm.
GO:0003677; Molecular function: DNA binding.
GO:0003887; Molecular function: DNA-directed DNA polymerase activity.
GO:0006261; Biological process: DNA-templated DNA replication.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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Pfam | PF07733; DNA_pol3_alpha; 1; |
PF00929; RNase_T; 1; | |
PF02811; PHP; 1; | |
PF01336; tRNA_anti; 1; | |
NCBIfam | TIGR00573; Dnaq; 1; |
TIGR01405; PolC_Gram_pos; 1; |
Additional information
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Size range | 1367-1638 amino acids |
Related rules | None |
Fusion | None |
Comments | LACLA has a weird insertion not found in other polC. |