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HAMAP rule MF_00362
General rule information
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| Accession | MF_00362 |
| Dates | 1-JUN-2001 (Created)
21-SEP-2023 (Last updated, Version 26) |
| Name | Ribosomal_uL10 |
| Scope(s) |
Bacteria |
| Template(s) | P0A7J3 (RL10_ECOLI); Q8VVE3 (RL10_THET8); P29394 (RL10_THEMA); P42923 (RL10_BACSU); [ Recover all ] |
| Triggered by |
HAMAP; MF_00362 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| case <OC:Bacteria> and not <OC:Cyanobacteriota> | |
| Identifier | RL10 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL10; |
| Gene name | Name=rplJ; |
| else case <OC:Cyanobacteriota> | |
| Identifier | RL10 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL10; |
| Gene name | Name=rplJ; Synonyms=rpl10; |
| end case | |
Comments
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| FUNCTION | Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. |
| SUBUNIT | Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. |
| SIMILARITY | Belongs to the universal ribosomal protein uL10 family. |
Keywords
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| case <FT:1> or <FT:2> | |
| Acetylation | |
| end case | |
| Ribonucleoprotein | |
| Ribosomal protein | |
| RNA-binding | |
| rRNA-binding | |
Gene Ontology
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| GO:0070180; Molecular function:large ribosomal subunit rRNA binding |
| GO:0006412; Biological process:translation |
Cross-references
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Features
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| From: RL10_ECOLI (P0A7J3) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <OC:Escherichia> or <OC:Shigella> | ||||||||||||
| MOD_RES | 37 | 37 | /note="N6-acetyllysine" | K | ||||||||
| MOD_RES | 105 | 105 | /note="N6-acetyllysine" | K | ||||||||
| end case | ||||||||||||
Additional information
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| Size range | 138-199 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Between 2 and 4 L12 dimers bind to L10, depending on the length of the C-terminus of L10. See PubMed:20467040. |