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HAMAP rule MF_00377

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General rule information [?]

Accession MF_00377
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 34)
Name DnaA_bact
Scope(s) Bacteria
Template(s) P03004 (DNAA_ECOLI); P05648 (DNAA_BACSU); [ Recover all ]
Triggered by HAMAP; MF_00377 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier DNAA
Protein name RecName: Full=Chromosomal replication initiator protein DnaA;
Gene name Name=dnaA;

Comments [?]

FUNCTIONPlays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
SIMILARITYBelongs to the DnaA family.

Keywords [?]

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0003688; Molecular function:DNA replication origin binding
GO:0006270; Biological process:DNA replication initiation
GO:0006275; Biological process:regulation of DNA replication
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF00308; Bac_DnaA; 1;
Pfam PF08299; Bac_DnaA_C; 1;
PRINTS PR00051; DNAA; 1;
NCBIfam TIGR00362; DnaA; 1;

Features [?]

From: DNAA_ECOLI (P03004)
Key From To Description Tag Condition FTGroup
BINDING 172 179 /ligand="ATP"

Additional information [?]

Size range 399-656 amino acids
Related rules None
Fusion Nter: None Cter: None

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