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Annotation rule MF_00377
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General rule information [?]

Accession MF_00377
Dates 1-JUN-2001 (Created)
26-SEP-2014 (Last updated, Version 30)
Name DnaA_bact
Scope
Bacteria
Templates P03004 (DNAA_ECOLI); P05648 (DNAA_BACSU): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
DNAA
Protein name
RecName: Full=Chromosomal replication initiator protein DnaA;
Gene name
dnaA

Comments [?]

Function Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
Subcellular location Cytoplasm.
Similarity Belongs to the DnaA family.

Keywords [?]

Cytoplasm
DNA replication
DNA-binding
ATP-binding
Nucleotide-binding

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0003688; Molecular function: DNA replication origin binding.
GO:0006270; Biological process: DNA replication initiation.
GO:0006275; Biological process: regulation of DNA replication.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF00308; Bac_DnaA; 1;
PF08299; Bac_DnaA_C; 1;
PRINTS PR00051; DNAA; 1;
TIGRFAMs TIGR00362; DnaA; 1;
PROSITE PS01008; DNAA; 1;

Features [?]

From: DNAA_ECOLI (P03004)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     172     179       ATP     [GSA]-x(2)-[GS]-x-G-K-[ST]  

Additional information [?]

Size range 399-656 amino acids
Related rules None
Fusion None


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