HAMAP rule MF_00377
General rule information
[?]
Accession | MF_00377 |
Dates | 1-JUN-2001 (Created) 19-NOV-2022 (Last updated, Version 33) |
Name | DnaA_bact |
Scope | Bacteria |
Templates | P03004 (DNAA_ECOLI); P05648 (DNAA_BACSU): [Recover all] |
Triggered by |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier |
|
Protein name |
|
Gene name |
|
Comments
[?]
Function | Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the DnaA family. |
Keywords
[?]
Gene Ontology
[?]
GO:0005524; Molecular function: ATP binding.
GO:0003688; Molecular function: DNA replication origin binding.
GO:0006270; Biological process: DNA replication initiation.
GO:0006275; Biological process: regulation of DNA replication.
GO:0005737; Cellular component: cytoplasm.
GO:0003688; Molecular function: DNA replication origin binding.
GO:0006270; Biological process: DNA replication initiation.
GO:0006275; Biological process: regulation of DNA replication.
GO:0005737; Cellular component: cytoplasm.
Cross-references
[?]
Pfam | PF00308; Bac_DnaA; 1; |
PF08299; Bac_DnaA_C; 1; | |
PRINTS | PR00051; DNAA; 1; |
TIGRFAMs | TIGR00362; DnaA; 1; |
PROSITE | PS01008; DNAA; 1; |
Features
[?]
From: DNAA_ECOLI (P03004) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 172 | 179 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 | [GSA]-x(2)-[GS]-x-G-K-[ST] |
Additional information
[?]
Size range | 399-656 amino acids |
Related rules | None |
Fusion | None |