HAMAP rule MF_00377
General rule information
[?]
| Accession | MF_00377 |
| Dates | 1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 34) |
| Name | DnaA_bact |
| Scope | Bacteria |
| Templates | P03004 (DNAA_ECOLI); P05648 (DNAA_BACSU): [Recover all] |
| Triggered by |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
| Identifier |
|
| Protein name |
|
||||
| Gene name |
|
Comments
[?]
| Function | Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. |
| Subcellular location | Cytoplasm. |
| Similarity | Belongs to the DnaA family. |
Keywords
[?]
Gene Ontology
[?]
GO:0005524; Molecular function: ATP binding.
GO:0003688; Molecular function: DNA replication origin binding.
GO:0006270; Biological process: DNA replication initiation.
GO:0006275; Biological process: regulation of DNA replication.
GO:0005737; Cellular component: cytoplasm.
GO:0003688; Molecular function: DNA replication origin binding.
GO:0006270; Biological process: DNA replication initiation.
GO:0006275; Biological process: regulation of DNA replication.
GO:0005737; Cellular component: cytoplasm.
Cross-references
[?]
| Pfam | PF00308; Bac_DnaA; 1; |
| PF08299; Bac_DnaA_C; 1; | |
| PRINTS | PR00051; DNAA; 1; |
| NCBIfam | TIGR00362; DnaA; 1; |
| PROSITE | PS01008; DNAA; 1; |
Features
[?]
| From: DNAA_ECOLI (P03004) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 172 | 179 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 | [GSA]-x(2)-[GS]-x-G-K-[ST] | ||||||||
Additional information
[?]
| Size range | 399-656 amino acids |
| Related rules | None |
| Fusion | None |