HAMAP rule MF_00383
General rule information
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| Accession | MF_00383 |
| Dates | 1-JUN-2001 (Created) 19-NOV-2022 (Last updated, Version 41) |
| Name | TF2B_arch |
| Scope | Archaea |
| Templates | P61998 (TF2B_PYRFU); P61999 (TF2B_PYRWO): [Recover all] |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). |
| Similarity | Belongs to the TFIIB family. |
Keywords
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case <FTGroup:1>
end case
Gene Ontology
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GO:0003700; Molecular function: DNA-binding transcription factor activity.
case <FTGroup:1>
GO:0008270; Molecular function: zinc ion binding.
end case
GO:0006355; Biological process: regulation of DNA-templated transcription.
GO:0006352; Biological process: DNA-templated transcription initiation.
GO:0006352; Biological process: DNA-templated transcription initiation.
Cross-references
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| Pfam | PF00382; TFIIB; 2; |
| PF08271; TF_Zn_Ribbon; 1; | |
| PRINTS | PR00685; TIFACTORIIB; 1; |
| PROSITE | PS00782; TFIIB; 2; |
| PS51134; ZF_TFIIB; 0-1; trigger=PRU00469; |
Features
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| From: TF2B_PYRFU (P61998) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| REPEAT | 114 | 197 | 1 | |||||||||
| REPEAT | 210 | 291 | 2 | |||||||||
| BINDING (Optional) | 7 | 7 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 | C | 1 | |||||||
| BINDING (Optional) | 10 | 10 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 | C | 1 | |||||||
| BINDING (Optional) | 26 | 26 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 | C | 1 | |||||||
| BINDING (Optional) | 29 | 29 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 | C | 1 | |||||||
Additional information
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| Size range | 287-339 amino acids |
| Related rules | None |
| Fusion | None |
| Comments | Intein deleted in METJA |