HAMAP logo

HAMAP rule MF_00393

Send feedback

General rule information [?]

Accession MF_00393
Dates 1-JUN-2001 (Created)
12-MAR-2024 (Last updated, Version 33)
Name Glyc3P_acyltrans
Scope(s) Bacteria
Template(s) P0A7A7 (PLSB_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00393 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier PLSB
Protein name RecName: Full=Glycerol-3-phosphate acyltransferase;
Gene name Name=plsB;

Comments [?]

CATALYTIC ACTIVITY Reaction=an acyl-CoA + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3- phosphate + CoA; Xref=Rhea:RHEA:15325, ChEBI:CHEBI:57287, ChEBI:CHEBI:57597, ChEBI:CHEBI:57970, ChEBI:CHEBI:58342; EC=;
PATHWAYPhospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP- diacylglycerol from sn-glycerol 3-phosphate: step 1/3.
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATIONCell membrane; Peripheral membrane protein; Cytoplasmic side.
else case <Property:Membrane=2>
SUBCELLULAR LOCATIONCell inner membrane; Peripheral membrane protein; Cytoplasmic side.
end case
DOMAINThe HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.
SIMILARITYBelongs to the GPAT/DAPAT family.

Keywords [?]

Gene Ontology [?]

GO:0004366; Molecular function:glycerol-3-phosphate O-acyltransferase activity
GO:0016024; Biological process:CDP-diacylglycerol biosynthetic process
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF01553; Acyltransferase; 1;
NCBIfam TIGR03703; plsB; 1;

Features [?]

Key From To Description Tag Condition FTGroup
MOTIF 305 310 /note="HXXXXD motif"

Additional information [?]

Size range 775-886 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments Possible wrong start in XANAC, XANCP and XYLFA. Second divergent plsB in MYCTU; not shown in alignment.

View rule in raw text format (no links)