HAMAP rule MF_00393
General rule information
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Accession | MF_00393 |
Dates | 1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 32) |
Name | Glyc3P_acyltrans |
Scope | Bacteria |
Template | P0A7A7 (PLSB_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Catalytic activity | RHEA:15325: an acyl-CoA + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + CoA
EC 2.3.1.15 |
Pathway | Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3. |
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location | Cell membrane; Peripheral membrane protein; Cytoplasmic side. |
else case <Property:Membrane=2>
Subcellular location | Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. |
end case
Domain | The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. |
Similarity | Belongs to the GPAT/DAPAT family. |
Keywords
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case defined <Property:Membrane> and <Property:Membrane=2>
end case
Cell membrane
Lipid biosynthesis
Lipid metabolism
Membrane
Phospholipid biosynthesis
Phospholipid metabolism
Transferase
Lipid biosynthesis
Lipid metabolism
Membrane
Phospholipid biosynthesis
Phospholipid metabolism
Transferase
Gene Ontology
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GO:0004366; Molecular function: glycerol-3-phosphate O-acyltransferase activity.
GO:0008654; Biological process: phospholipid biosynthetic process.
GO:0005886; Cellular component: plasma membrane.
GO:0008654; Biological process: phospholipid biosynthetic process.
GO:0005886; Cellular component: plasma membrane.
Cross-references
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Features
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From: PLSB_ECOLI (P0A7A7) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
MOTIF | 305 | 310 | HXXXXD motif |
Additional information
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Size range | 775-886 amino acids |
Related rules | None |
Fusion | None |
Comments | Possible wrong start in XANAC, XANCP and XYLFA. Second divergent plsB in MYCTU; not shown in alignment. |