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Annotation rule MF_00393 |
General rule information
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Accession |
MF_00393 |
Dates |
1-JUN-2001 (Created) 18-NOV-2019 (Last updated, Version 31) |
Propagated annotation
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Identifier, protein and gene names
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Protein name |
RecName:
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Full=Glycerol-3-phosphate acyltransferase;
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Short=GPAT;
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EC 2.3.1.15;
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Catalytic activity |
RHEA:15325: an acyl-CoA + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + CoA
EC 2.3.1.15
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Pathway |
Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3. |
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location |
Cell membrane; Peripheral membrane protein; Cytoplasmic side. |
else case <Property:Membrane=2>
Subcellular location |
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. |
end case
Domain |
The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. |
Similarity |
Belongs to the GPAT/DAPAT family. |
case defined <Property:Membrane> and <Property:Membrane=2>
end case
GO:0004366; Molecular function: glycerol-3-phosphate O-acyltransferase activity.
GO:0008654; Biological process: phospholipid biosynthetic process.
GO:0005886; Cellular component: plasma membrane.
From: PLSB_ECOLI (P0A7A7) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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MOTIF
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305
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310
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HXXXXD motif
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Additional information
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Size range |
775-886 amino acids |
Related rules |
None |
Fusion |
None |
Comments |
Possible wrong start in XANAC, XANCP and XYLFA. Second divergent plsB in MYCTU; not shown in alignment. |