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Annotation rule MF_00406 |
General rule information
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Accession |
MF_00406 |
Dates |
1-JUN-2001 (Created) 18-NOV-2019 (Last updated, Version 30) |
Propagated annotation
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Identifier, protein and gene names
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Protein name |
RecName:
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Full=3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ;
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EC 4.2.1.59;
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AltName:
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Full=(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase;
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Short=(3R)-hydroxymyristoyl-ACP dehydrase;
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AltName:
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Full=Beta-hydroxyacyl-ACP dehydratase;
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Function |
Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. |
Catalytic activity |
RHEA:13097: a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O
EC 4.2.1.59
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case <OC:Escherichia> or <OC:Shigella>
end case
Subcellular location |
Cytoplasm. |
case <OC:Escherichia> or <OC:Shigella>
Ptm |
The N-terminus is blocked. |
end case
Similarity |
Belongs to the thioester dehydratase family. FabZ subfamily. |
GO:0016836; Molecular function: hydro-lyase activity.
GO:0006633; Biological process: fatty acid biosynthetic process.
GO:0009245; Biological process: lipid A biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
From: FABZ_ECOLI (P0A6Q6) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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ACT_SITE
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54
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54
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H
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Additional information
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Size range |
132-181 amino acids |
Related rules |
MF_00405 (FABA) |
Fusion |
Nter: MF_00388 (lpxC); Cter: None |
Comments |
Possible wrong start in SYNY3 |