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Annotation rule MF_00413 |
General rule information
[?]
Accession |
MF_00413 |
Dates |
1-JUN-2001 (Created) 18-NOV-2019 (Last updated, Version 23) |
Scope |
Bacteria; Gammaproteobacteria |
Propagated annotation
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Identifier, protein and gene names
[?]
case <OC:Enterobacterales>
Protein name |
RecName:
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Full=Sulfur carrier protein TusA;
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AltName:
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Full=Sulfur mediator TusA;
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AltName:
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Full=Sulfur transfer protein TusA;
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AltName:
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Full=tRNA 2-thiouridine synthesizing protein A;
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else
Protein name |
RecName:
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Full=Sulfur carrier protein TusA;
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end case
case <OC:Enterobacterales>
Function |
Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin. |
Subunit |
Interacts with IscS. |
Pathway |
tRNA modification. |
else
Function |
Sulfur carrier protein which probably makes part of a sulfur-relay system. |
end case
Subcellular location |
Cytoplasm. |
Similarity |
Belongs to the sulfur carrier protein TusA family. |
case <OC:Enterobacterales>
end case
GO:0097163; Molecular function: sulfur carrier activity.
case <OC:Enterobacterales>
end case
From: TUSA_ECOLI (P0A890) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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ACT_SITE
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19
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19
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Cysteine persulfide intermediate
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C
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Additional information
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Size range |
76-84 amino acids |
Related rules |
None |
Fusion |
None |