HAMAP rule MF_00414
General rule information
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| Accession | MF_00414 |
| Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 38) |
| Name | UbiB |
| Scope(s) |
Bacteria |
| Template(s) | P0A6A0 (UBIB_ECOLI); O07443 (UBIB_PROST); [ Recover all ] |
| Triggered by |
HAMAP; MF_00414 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | UBIB |
| Protein name | RecName: Full=Probable protein kinase UbiB; EC=2.7.-.-; AltName: Full=Ubiquinone biosynthesis protein UbiB; |
| Gene name | Name=ubiB; |
Comments
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| FUNCTION | Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. |
| PATHWAY | Cofactor biosynthesis; ubiquinone biosynthesis [regulation]. |
| case (not defined <Property:Membrane> or <Property:Membrane=1>) and <Feature:Transmembrane==1> | |
| SUBCELLULAR LOCATION | Cell membrane; Single-pass membrane protein. |
| end case | |
| case (not defined <Property:Membrane> or <Property:Membrane=1>) and <Feature:Transmembrane>1> | |
| SUBCELLULAR LOCATION | Cell membrane; Multi-pass membrane protein. |
| end case | |
| case defined <Property:Membrane> and <Property:Membrane=2> and <Feature:Transmembrane==1> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Single-pass membrane protein. |
| end case | |
| case defined <Property:Membrane> and <Property:Membrane=2> and <Feature:Transmembrane>1> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein. |
| end case | |
| SIMILARITY | Belongs to the ABC1 family. UbiB subfamily. |
Keywords
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| ATP-binding | |
| case defined <Property:Membrane> and <Property:Membrane=2> | |
| Cell inner membrane | |
| end case | |
| Cell membrane | |
| Kinase | |
| Membrane | |
| Nucleotide-binding | |
| Transferase | |
| Transmembrane | |
| Ubiquinone biosynthesis | |
| Transmembrane helix | |
Gene Ontology
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| GO:0004672; Molecular function:protein kinase activity |
| GO:0010795; Biological process:regulation of ubiquinone biosynthetic process |
| GO:0005886; Cellular component:plasma membrane |
Cross-references
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| PROSITE | PS00107; PROTEIN_KINASE_ATP; 1; |
| PROSITE | PS50011; PROTEIN_KINASE_DOM; 1; |
| Pfam | PF03109; ABC1; 1; |
| NCBIfam | TIGR01982; UbiB; 1; |
| General | Transmembrane; -; 1-3; |
Features
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| From: UBIB_ECOLI (P0A6A0) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | 124 | 502 | /note="Protein kinase" | |||||||||
| BINDING | 130 | 138 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
|||||||||
| ACT_SITE | 288 | 288 | /note="Proton acceptor" | D | ||||||||
| BINDING | 153 | 153 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
K | ||||||||
Additional information
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| Size range | 503-557 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |